SCHEMBL5496418

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5496427	1.00	TUBB1 (1.00)	TUBB1APPCYP1A2CYP1A1CYP1B1
	SCHEMBL30873010	1.00	TUBB1 (1.00)	TUBB1APPCYP1A2CYP1A1CYP1B1
	SCHEMBL3393305	0.91	TUBB1 (0.83)	TUBB1APPCYP1A2TUBB4ATUBB
	Combretastatin A4 SCHEMBL8188814	0.91	TUBB1 (0.85)	TUBB1APPCYP1A2CYP1A1CYP1B1
	SCHEMBL30609589	0.88	TUBB1 (0.78)	TUBB1APPCYP1A2CYP1A1TUBB4A
	SCHEMBL15633028	0.88	TUBB1 (0.78)	TUBB1APPCYP1A2CYP1A1TUBB4A
	SCHEMBL15633027	0.88	TUBB1 (0.78)	TUBB1APPCYP1A2CYP1A1TUBB4A
	SCHEMBL6781126	0.86	NQO2 (0.78)	TUBB1APPCYP1A1CYP1B1TUBB4A
	SCHEMBL6781119	0.86	NQO2 (0.78)	TUBB1APPCYP1A1CYP1B1TUBB4A
	SCHEMBL2945375	0.86	NFE2L2 (0.75)	TUBB1APPCYP1A2CYP1A1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.