Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 10/20 | 0.74 |
| ▸ | CYP1B1 | Q16678 | 10/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.74 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.74 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.68 |
| ▸ | TUBB | P07437 | 5/20 | 0.68 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.68 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.68 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.68 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.68 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.68 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.68 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.68 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.68 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.68 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.68 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.68 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.68 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.68 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5498223 | 1.00 | CYP1A1 (0.74) | CYP1A1CYP1B1CYP1A2NFE2L2TUBB4A | |
| SCHEMBL19583362 | 0.96 | CYP1A1 (0.79) | CYP1A1CYP1B1CYP1A2NFE2L2TUBB4A | |
| SCHEMBL19583363 | 0.96 | CYP1A1 (0.79) | CYP1A1CYP1B1CYP1A2NFE2L2TUBB4A | |
| SCHEMBL3753811 | 0.94 | CYP1A1 (0.77) | CYP1A1CYP1B1CYP1A2NFE2L2TUBB4A | |
| SCHEMBL13443550 | 0.94 | CYP1A1 (0.77) | CYP1A1CYP1B1CYP1A2NFE2L2TUBB4A | |
| SCHEMBL16274063 | 0.89 | CYP1A1 (0.70) | CYP1A1CYP1B1CYP1A2NFE2L2TUBB4A | |
| SCHEMBL13409617 | 0.88 | RELA (0.70) | CYP1A1CYP1B1CYP1A2NFE2L2TUBB4A | |
| SCHEMBL17589619 | 0.86 | CYP1A1 (0.66) | CYP1A1CYP1B1CYP1A2NFE2L2TUBB4A | |
| SCHEMBL5495428 | 0.85 | CYP1A2 (1.00) | CYP1A1CYP1B1CYP1A2NFE2L2TUBB4A | |
| SCHEMBL13926063 | 0.85 | CYP1A1 (0.86) | CYP1A1CYP1B1CYP1A2NFE2L2TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9925153-B2 | Therapeutic agents for skin diseases and conditions | STC.UNM (US) | 2018-03-27 | — | — | US | disclosed |
| US-20160287531-A1 | THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS | STC.UNM | 2016-10-06 | — | — | US | disclosed |
| WO-2015085143-A2 | THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS | STC.UNM (US) | 2015-06-11 | — | — | WO | disclosed |
| US-8980954-B2 | Substituted cis- and trans-stilbenes as therapeutic agents | STC.UNM (US) | 2015-03-17 | — | — | US | disclosed |
| US-20130178536-A1 | SUBSTITUTED CIS- AND TRANS-STILBENES AS THERAPEUTIC AGENTS | STC.UNM (US) | 2013-07-11 | — | — | US | disclosed |
| US-20070249647-A1 | Substituted CIS- and trans-stilbenes as therapeutic agents | REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160287531-A1 | THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS | CUTA, TSLP, ELANE | CYP1A1 1445/4885CYP1B1 1256/4885CYP1A2 1332/4885 |
| US-20070249647-A1 | Substituted CIS- and trans-stilbenes as therapeutic agents | TGFB1, VHL, TMSB10 | CYP1A1 874/4885CYP1B1 713/4885CYP1A2 1159/4885 |
| US-20130178536-A1 | SUBSTITUTED CIS- AND TRANS-STILBENES AS THERAPEUTIC AGENTS | PSEN1, TERT, PSEN2 | CYP1A1 809/4885CYP1B1 936/4885CYP1A2 1201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.