Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 15/20 | 1.00 |
| ▸ | CYP1A1 | P04798 | 15/20 | 1.00 |
| ▸ | CYP1B1 | Q16678 | 15/20 | 1.00 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.77 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.77 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.77 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.77 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.77 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.77 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.77 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.77 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.77 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.77 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495431 | 1.00 | CYP1A2 (1.00) | CYP1A2CYP1A1CYP1B1NFE2L2CYP19A1 | |
| SCHEMBL13926063 | 0.93 | CYP1A1 (0.86) | CYP1A2CYP1A1CYP1B1NFE2L2CYP19A1 | |
| SCHEMBL30342416 | 0.91 | CYP1A2 (0.83) | CYP1A2CYP1A1CYP1B1NFE2L2CYP19A1 | |
| SCHEMBL25706432 | 0.90 | CYP1A2 (1.00) | CYP1A2CYP1A1CYP1B1NFE2L2CYP19A1 | |
| SCHEMBL1976945 | 0.90 | CYP1A2 (0.81) | CYP1A2CYP1A1CYP1B1NFE2L2CYP19A1 | |
| SCHEMBL14401250 | 0.89 | CYP1A2 (1.00) | CYP1A2CYP1A1CYP1B1NFE2L2CYP19A1 | |
| SCHEMBL5498411 | 0.89 | CYP1A2 (1.00) | CYP1A2CYP1A1CYP1B1NFE2L2CYP19A1 | |
| SCHEMBL5498406 | 0.89 | CYP1A2 (1.00) | CYP1A2CYP1A1CYP1B1NFE2L2CYP19A1 | |
| SCHEMBL19583362 | 0.89 | CYP1A1 (0.79) | CYP1A2CYP1A1CYP1B1NFE2L2CYP19A1 | |
| SCHEMBL19583363 | 0.89 | CYP1A1 (0.79) | CYP1A2CYP1A1CYP1B1NFE2L2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220023172-A1 | COSMETIC COMPOSITIONS AND METHODS OF USE | TRUJILLO KRISTINA (US) | 2022-01-27 | — | — | US | disclosed |
| US-20200397676-A1 | COSMETIC COMPOSITIONS AND METHODS OF USE | K&K BIOTECH (US) | 2020-12-24 | — | — | US | disclosed |
| WO-2020112998-A1 | COSMETIC COMPOSITIONS AND METHODS OF USE | STC.UNM (US) | 2020-06-04 | — | — | WO | disclosed |
| US-20190160021-A1 | Substituted Stilbenes as Inhibitors of NF-kappaB and Activators of Nrf2 | STC UNM (US) | 2019-05-30 | — | — | US | disclosed |
| US-9925153-B2 | Therapeutic agents for skin diseases and conditions | STC.UNM (US) | 2018-03-27 | — | — | US | disclosed |
| US-20160287531-A1 | THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS | STC.UNM | 2016-10-06 | — | — | US | disclosed |
| US-8980954-B2 | Substituted cis- and trans-stilbenes as therapeutic agents | STC.UNM (US) | 2015-03-17 | — | — | US | disclosed |
| US-20130178536-A1 | SUBSTITUTED CIS- AND TRANS-STILBENES AS THERAPEUTIC AGENTS | STC.UNM (US) | 2013-07-11 | — | — | US | disclosed |
| US-20070249647-A1 | Substituted CIS- and trans-stilbenes as therapeutic agents | REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190160021-A1 | Substituted Stilbenes as Inhibitors of NF-kappaB and Activators of Nrf2 | NFKBIA, NFE2L2, NFKB2 | CYP1A2 2222/4885CYP1A1 1557/4885CYP1B1 542/4885 |
| US-20160287531-A1 | THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS | CUTA, TSLP, ELANE | CYP1A2 1332/4885CYP1A1 1445/4885CYP1B1 1256/4885 |
| US-20220023172-A1 | COSMETIC COMPOSITIONS AND METHODS OF USE | NFKBIA, IKBKB, NFKB2 | CYP1A2 2168/4885CYP1A1 1728/4885CYP1B1 292/4885 |
| US-20070249647-A1 | Substituted CIS- and trans-stilbenes as therapeutic agents | TGFB1, VHL, TMSB10 | CYP1A2 1159/4885CYP1A1 874/4885CYP1B1 713/4885 |
| US-20130178536-A1 | SUBSTITUTED CIS- AND TRANS-STILBENES AS THERAPEUTIC AGENTS | PSEN1, TERT, PSEN2 | CYP1A2 1201/4885CYP1A1 809/4885CYP1B1 936/4885 |
| US-20200397676-A1 | COSMETIC COMPOSITIONS AND METHODS OF USE | KEAP1, NFE2L2, NQO1 | CYP1A2 1921/4885CYP1A1 1557/4885CYP1B1 270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.