SCHEMBL5498760

SCHEMBL5498760

NCCCC[C@@H](N)C(N)=O

nearest known ligand 0.67

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.67
RNPEP Q9H4A4 1/20 0.46
GNAI3 P08754 1/20 0.46
GNAO1 P09471 1/20 0.46
GNAI1 P63096 1/20 0.46
DPP7 Q9UHL4 9/20 0.44
DPP8 Q6V1X1 5/20 0.44
DPP9 Q86TI2 5/20 0.44
DPP4 P27487 3/20 0.44
CPB2 Q96IY4 2/20 0.42
FAP Q12884 1/20 0.40
MMP2 P08253 1/20 0.39
ARG1 P05089 1/20 0.39
ARG2 P78540 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL363001 1.00 GSR (0.67) GSRRNPEPGNAI3GNAO1GNAI1
SCHEMBL29483946 1.00 GSR (0.67) GSRRNPEPGNAI3GNAO1GNAI1
SCHEMBL358119 1.00 GSR (0.67) GSRRNPEPGNAI3GNAO1GNAI1
SCHEMBL362251 0.98 GSR (0.64) GSRRNPEPGNAI3GNAO1GNAI1
Hydrochloric Acid SCHEMBL14831148 0.98 GSR (0.64) GSRRNPEPGNAI3GNAO1GNAI1
SCHEMBL24722227 0.98 GSR (0.64) GSRRNPEPGNAI3GNAO1GNAI1
Hydrochloric Acid SCHEMBL14831515 0.98 GSR (0.64) GSRRNPEPGNAI3GNAO1GNAI1
Hydrochloric Acid SCHEMBL8497748 0.98 GSR (0.64) GSRRNPEPGNAI3GNAO1GNAI1
SCHEMBL22163010 0.98 GSR (0.64) GSRRNPEPGNAI3GNAO1GNAI1
SCHEMBL361149 0.98 GSR (0.64) GSRRNPEPGNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240002438-A1 MELANOCORTIN LIGANDS AND METHODS OF USE THEREOF THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES 2024-01-04 US claimed
EP-2709645-B1 IMPROVED PEPTIDE PHARMACEUTICALS EUMEDERIS PHARMACEUTICALS INC (US) 2023-08-09 EP claimed
EP-4696699-A1 ? OPIOID RECEPTOR AGONIST AND USE THEREOF Chengdu Aoda Biotechnology Co., Ltd. (CN) 2026-02-18 EP disclosed
US-12552836-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases PROTAGONIST THERAPEUTICS, INC. (US) 2026-02-17 US disclosed
US-20260007756-A1 COMPOUND AND USE THEREOF COHERENT BIOPHARMA SUZHOU LTD (CN) 2026-01-08 US disclosed
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
US-20250304624-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. 2025-10-02 US disclosed
EP-4512426-A1 COMPOUND AND USE THEREOF Coherent Biopharma (Suzhou), Limited (CN) 2025-02-26 EP disclosed
CN-119031938-A Compounds and uses 同宜医药(苏州)有限公司 2024-11-26 CN disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 WO disclosed
WO-2024073622-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING EPHRIN TYPE-A RECEPTOR 2 AND USES THEREOF RAYZEBIO, INC. (US) 2024-04-04 WO disclosed
WO-2022112865-A1 MULTI-SPECIFIC HUMAN ALBUMIN NANOPARTICLES DECORATED WITH ANTIBODY FRAGMENTS AND LOADED WITH CYTOTOXICS ANBITION S.R.L. (IT) 2022-06-02 WO disclosed
WO-2022112866-A1 USE OF MULTI-SPECIFIC HUMAN ALBUMIN NANOPARTICLES DECORATED WITH ANTIBODY FRAGMENTS AND LOADED WITH CYTOTOXICS ANBITION S.R.L. (IT) 2022-06-02 WO disclosed
WO-2022026633-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2022-02-03 WO disclosed
US-11149066-B2 Thrombospondin 1-binding peptide DAIICHI SANKYO COMPANY, LIMITED (JP) 2021-10-19 US disclosed
US-20200131230-A1 THROMBOSPONDIN 1-BINDING PEPTIDE DAIICHI SANKYO COMPANY, LIMITED (JP) 2020-04-30 US disclosed
WO-2015034920-A2 GRANULOCYTE MACROPHAGE COLONY-STIMULATING FACTOR COMPOSITIONS SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2015-03-12 WO disclosed
WO-2010053548-A2 PTHR1 RECEPTOR COMPOUNDS ANCHOR THERAPEUTICS, INC. (US) 2010-05-14 WO disclosed
EP-1100816-B1 AEROTHRICIN ANALOGS, THEIR PREPARATION AND USE BASILEA PHARMACEUTICA AG (CH) 2007-08-08 EP disclosed
US-6489440-B1 Cyclic compounds BASILEA PHARMACEUTICA AG (CH) 2002-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11149066-B2 Thrombospondin 1-binding peptide SERPINC1, TEK, ARGLU1 GSR 4846/4885RNPEP 364/4885GNAI3 2915/4885
US-20200131230-A1 THROMBOSPONDIN 1-BINDING PEPTIDE SERPINC1, TEK, ARGLU1 GSR 4846/4885RNPEP 364/4885GNAI3 2915/4885
US-12552836-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases IL23R, IL17A, IL36G GSR 4052/4885RNPEP 323/4885GNAI3 2682/4885
US-20260007756-A1 COMPOUND AND USE THEREOF FOLH1, TRPV6, FOLR1 GSR 2517/4885RNPEP 2363/4885GNAI3 3357/4885
US-20250304624-A1 CONJUGATED HEPCIDIN MIMETICS HAMP, VIP, HDGF GSR 2345/4885RNPEP 223/4885GNAI3 2385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.