Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 12/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 11/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4948918 | 0.81 | LMNA (0.43) | ADORA2AADORA2BADORA1ADORA3ALDH1A1 | |
| SCHEMBL5498228 | 0.80 | LMNA (0.37) | ADORA2AADORA2BADORA1ADORA3ALDH1A1 | |
| SCHEMBL5492971 | 0.80 | NT5E (0.38) | ADORA2AADORA2BADORA1ADORA3ALDH1A1 | |
| SCHEMBL5735963 | 0.79 | LMNA (0.35) | ADORA2AADORA1ADORA3ALDH1A1LMNA | |
| SCHEMBL9404059 | 0.78 | LMNA (0.34) | ADORA2AADORA1ADORA3ALDH1A1LMNA | |
| SCHEMBL4834707 | 0.76 | PDE4A (0.37) | ADORA2AADORA2BADORA1ADORA3LMNA | |
| SCHEMBL6386486 | 0.76 | PDE4A (0.37) | ADORA2AADORA2BADORA1ADORA3LMNA | |
| SCHEMBL4833723 | 0.72 | ADORA3 (0.37) | ADORA2AADORA2BADORA1ADORA3LMNA | |
| SCHEMBL5502159 | 0.70 | ALDH1A1 (0.70) | ADORA2AADORA2BADORA1ADORA3ALDH1A1 | |
| SCHEMBL1120685 | 0.70 | HINT1 (0.43) | ADORA3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446413-A4 | SYNTHESIS OF 2-ARALKOXY ADENOSINES AND 2-ALKOXYADENOSINES | KING PHARMACEUTICALS RES & DEV (US) | 2007-10-17 | — | — | EP | disclosed |
| EP-1446413-A1 | SYNTHESIS OF 2-ARALKOXY ADENOSINES AND 2-ALKOXYADENOSINES | King Pharmaceuticals Research and Development Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003035662-A1 | SYNTHESIS OF 2-ARALKOXY ADENOSINES AND 2-ALKOXYADENOSINES | KING PHARMACEUTICALS RESEARCH & DEVELOPMENT, INC. (US) | 2003-05-01 | — | — | WO | disclosed |