Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.33 |
| ▸ | AHCY | P23526 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6386486 | 1.00 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL4833723 | 0.88 | ADORA3 (0.37) | ADORA3ADORA2AADORA1TSHRLMNA | |
| SCHEMBL30544925 | 0.88 | ADORA2A (0.49) | ADORA3ADORA2AADORA1TSHRLMNA | |
| SCHEMBL4948918 | 0.87 | LMNA (0.43) | ADORA3ADORA2AADORA1LMNAADORA2B | |
| SCHEMBL6909391 | 0.86 | NPEPPS (0.39) | LMNA | |
| SCHEMBL5498228 | 0.86 | LMNA (0.37) | ADORA3ADORA2AADORA1LMNAADORA2B | |
| SCHEMBL5492971 | 0.86 | NT5E (0.38) | ADORA3ADORA2AADORA1LMNAHSP90B1 | |
| SCHEMBL9404373 | 0.85 | LMNA (0.35) | ADORA3ADORA2AADORA1LMNAAHCY | |
| SCHEMBL5735963 | 0.85 | LMNA (0.35) | ADORA3ADORA2AADORA1LMNA | |
| SCHEMBL7068201 | 0.84 | ADORA2A (0.35) | PDE4APDE4BPDE4CPDE4DADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345164-B2 | Production method of 5′-acyloxynucleoside compound | AJINOMOTO CO., INC. (JP) | 2008-03-18 | — | — | US | disclosed |
| US-20060014944-A1 | Processes for production of nucleosides | AJINOMOTO CO., INC. (JP) | 2006-01-19 | — | — | US | disclosed |
| EP-1589027-A1 | PROCESSES FOR PRODUCTION OF NUCLEOSIDES | Ajinomoto Co., Inc. (JP) | 2005-10-26 | — | — | EP | disclosed |
| US-20040230053-A1 | Production method of 5'-acyloxynucleoside compound | AJINOMOTO CO., INC. (JP) | 2004-11-18 | — | — | US | disclosed |
| EP-1471071-A1 | Production method of 5'-acyloxynucleoside compound | Ajinmoto Co., Inc. (JP) | 2004-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014944-A1 | Processes for production of nucleosides | NUDT1, NT5C3B, DNTT | PDE4A 1682/4885PDE4B 1250/4885PDE4C 1245/4885 |
| US-20040230053-A1 | Production method of 5'-acyloxynucleoside compound | ALKBH2, DUT, ALKBH1 | PDE4A 1200/4885PDE4B 868/4885PDE4C 1095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.