Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | GPR4 | P46093 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499921 | 0.92 | IDO1 (0.43) | GPR84OPRM1OPRK1HTR1ADRD2 | |
| SCHEMBL7428659 | 0.86 | TACR1 (0.42) | OPRM1OPRK1HTR1ADRD2DRD4 | |
| SCHEMBL5499307 | 0.84 | SIGMAR1 (0.49) | SLC6A4SLC6A2GPR4KCNH2 | |
| SCHEMBL5500263 | 0.83 | KCNH2 (0.41) | OPRM1OPRK1OPRL1TACR1SLC6A4 | |
| SCHEMBL5495230 | 0.82 | EPHX1 (0.39) | TACR1GPR4KCNH2 | |
| SCHEMBL5502520 | 0.81 | KCNH2 (0.41) | DRD2TACR1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7426590 | 0.78 | SLC6A2 (0.44) | OPRM1OPRL1TACR1SLC6A4SLC6A2 | |
| SCHEMBL5500050 | 0.76 | KCNH2 (0.43) | OPRM1OPRK1OPRL1TACR1GPR4 | |
| SCHEMBL5499282 | 0.76 | SIGMAR1 (0.51) | SLC6A4SLC6A2 | |
| SCHEMBL5500092 | 0.75 | FFAR4 (0.43) | TACR1SLC6A4SLC6A2KCNH2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765779-A1 | NEW SUBSTITUTED PIPERIDINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005121092-A1 | NEW SUBSTITUTED PIPERIDINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2005-12-22 | — | — | WO | disclosed |