Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 12/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499300 | 0.92 | SLC6A2 (0.45) | FFAR4SLC6A2SLC6A4RENCYP3A4 | |
| SCHEMBL2785289 | 0.86 | FFAR4 (0.43) | FFAR4SLC6A2SLC6A4TACR1P2RX7 | |
| SCHEMBL5499318 | 0.83 | KCNH2 (0.33) | FFAR4SLC6A2SLC6A4RENCYP3A4 | |
| SCHEMBL5500299 | 0.83 | TAAR1 (0.42) | SLC6A2SLC6A4RENCYP3A4KCNH2 | |
| SCHEMBL5495293 | 0.82 | P2RX7 (0.38) | FFAR4SLC6A2SLC6A4KCNH2TACR1 | |
| SCHEMBL5499100 | 0.79 | KCNH2 (0.41) | SLC6A2SLC6A4RENCYP3A4KCNH2 | |
| SCHEMBL5493818 | 0.78 | FFAR4 (0.41) | FFAR4SLC6A2SLC6A4RENCYP3A4 | |
| SCHEMBL5499363 | 0.78 | TACR1 (0.43) | FFAR4SLC6A2SLC6A4TACR1P2RX7 | |
| SCHEMBL5495138 | 0.77 | KCNH2 (0.37) | SLC6A2SLC6A4RENKCNH2TACR1 | |
| SCHEMBL5498980 | 0.75 | GPR84 (0.46) | SLC6A2SLC6A4KCNH2TACR1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765779-A1 | NEW SUBSTITUTED PIPERIDINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2007-03-28 | — | — | EP | claimed |
| WO-2005121092-A1 | NEW SUBSTITUTED PIPERIDINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2005-12-22 | — | — | WO | claimed |