Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.60 |
| ▸ | HTR6 | P50406 | 1/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.52 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylphenylsulfone SCHEMBL78253 | 0.97 | PTGS2 (0.62) | PTGS2HTR6ENPP2PSIP1ALDH1A1 | |
| Methylphenylsulfone SCHEMBL1332357 | 0.97 | PTGS2 (0.62) | PTGS2HTR6ENPP2PSIP1ALDH1A1 | |
| Methylphenylsulfone SCHEMBL28158010 | 0.92 | PTGS2 (0.58) | PTGS2HTR6ENPP2PSIP1ALDH1A1 | |
| Methylphenylsulfone SCHEMBL28046614 | 0.92 | PTGS2 (0.58) | PTGS2HTR6ENPP2PSIP1ALDH1A1 | |
| Methylphenylsulfone SCHEMBL28288198 | 0.92 | PTGS2 (0.58) | PTGS2HTR6ENPP2PSIP1ALDH1A1 | |
| Methylphenylsulfone SCHEMBL28097901 | 0.92 | PTGS2 (0.58) | PTGS2HTR6ENPP2PSIP1ALDH1A1 | |
| Methylphenylsulfone SCHEMBL1925243 | 0.89 | ALDH1A1 (0.59) | PTGS2HTR6ENPP2PSIP1ALDH1A1 | |
| Methylphenylsulfone SCHEMBL27930437 | 0.89 | PTGS2 (0.56) | PTGS2HTR6ENPP2PSIP1ALDH1A1 | |
| Methylphenylsulfone SCHEMBL11698567 | 0.89 | PTGS2 (0.56) | PTGS2HTR6ENPP2PSIP1ALDH1A1 | |
| SCHEMBL17936671 | 0.87 | HTR6 (0.70) | PTGS2HTR6ENPP2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166568-B1 | Compositions and methods to inhibit formation of the C5b-9 complex of complement | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 2007-01-23 | — | — | US | disclosed |
| EP-0693556-B1 | TRANSGLUTAMINASE ORIGINATING IN JAPANESE OYSTER | AJINOMOTO KK (JP) | 2004-10-06 | — | — | EP | disclosed |
| US-20030166565-A1 | Compositions and methods to inhibit formation of the C5b-9 complex of complement | OKLAHOMA MEDICAL RESEARCH FOUNDATION | 2003-09-04 | — | — | US | disclosed |
| EP-1053254-A2 | COMPOSITIONS AND METHODS TO INHIBIT FORMATION OF THE C5b-9 COMPLEX OF COMPLEMENT | Oklahoma Medical Research Foundation (US) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040115-A9 | COMPOSITIONS AND METHODS TO INHIBIT FORMATION OF THE C5b-9 COMPLEX OF COMPLEMENT | OKLAHOMA MED RES FOUND (US) | 2000-01-20 | — | — | WO | disclosed |
| WO-1999040115-A2 | COMPOSITIONS AND METHODS TO INHIBIT FORMATION OF THE C5b-9 COMPLEX OF COMPLEMENT | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 1999-08-12 | — | — | WO | disclosed |
| US-5859339-A | HYBRIDIZED POLYNUCLEOTIDES COMPRISING A PROMOTER SEQUENCE GREATER THAN ABOUT FIFTY NUCLEOTIDES LINKED TO A HETEROLOGOUS POLYNUCLEOTIDE SEQUENCE USED TO PRODUCE TRANSGENIC PLANTS RESISTANT TO THE PATHOGEN. | THE REAGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0809513-A4 | ENCAPSIDATED RECOMBINANT POLIOVIRUS NUCLEIC ACID | UAB RESEARCH FOUNDATION (US) | 1998-05-27 | — | — | EP | disclosed |
| US-5736356-A | CULTIVATION OF TRANSFORMED CELL AS GELLING AGENT FOR GELATION OF PROTEIN SOLUTION OR SLURRY | AJINOMOTO CO., INC. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0809513-A1 | ENCAPSIDATED RECOMBINANT POLIOVIRUS NUCLEIC ACID | THE UAB RESEARCH FOUNDATION (US) | 1997-12-03 | — | — | EP | disclosed |
| EP-0805860-A2 | PROCEDURES AND MATERIALS FOR CONFERRING DISEASE RESISTANCE IN PLANTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-11-12 | — | — | EP | disclosed |
| EP-0433088-B1 | Monoclonal antibodies reactive with a human atheroma associated antigen | LILLY CO ELI (US) | 1997-06-18 | — | — | EP | disclosed |
| US-5597726-A | Monoclonal antibodies reactive with a human atheroma associated antigen | ELI LILLY AND COMPANY (US) | 1997-01-28 | — | — | US | disclosed |
| WO-1996025173-A1 | ENCAPSIDATED RECOMBINANT POLIOVIRUS NUCLEIC ACID | THE UAB RESEARCH FOUNDATION (US) | 1996-08-22 | — | — | WO | disclosed |
| WO-1996022375-A2 | PROCEDURES AND MATERIALS FOR CONFERRING DISEASE RESISTANCE IN PLANTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-07-25 | — | — | WO | disclosed |
| EP-0693556-A1 | TRANSGLUTAMINASE ORIGINATING IN JAPANESE OYSTER | Ajinomoto Co., Inc. (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5196324-A | Use in diagnosis of atherosclerosis | ELI LILLY AND COMPANY (US) | 1993-03-23 | — | — | US | disclosed |
| EP-0433088-A1 | Monoclonal antibodies reactive with a human atheroma associated antigen | ELI LILLY AND COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |