Methylphenylsulfone

Methylphenylsulfone

SCHEMBL78253

CS(=O)(=O)c1ccccc1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 8/20 0.62
HTR6 P50406 1/20 0.58
ENPP2 Q13822 2/20 0.55
PSIP1 O75475 1/20 0.55
ALDH1A1 P00352 1/20 0.52
HSD17B10 Q99714 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA3 P07451 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
CA5A P35218 1/20 0.52
CA7 P43166 1/20 0.52
PLA2G7 Q13093 1/20 0.52
CA9 Q16790 1/20 0.52
CA13 Q8N1Q1 1/20 0.52
CA14 Q9ULX7 1/20 0.52
CA5B Q9Y2D0 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylphenylsulfone SCHEMBL1332357 1.00 PTGS2 (0.62) PTGS2HTR6ENPP2PSIP1ALDH1A1
Methylphenylsulfone SCHEMBL5499087 0.97 PTGS2 (0.60) PTGS2HTR6ENPP2PSIP1ALDH1A1
Methylphenylsulfone SCHEMBL28046614 0.94 PTGS2 (0.58) PTGS2HTR6ENPP2PSIP1ALDH1A1
Methylphenylsulfone SCHEMBL28158010 0.94 PTGS2 (0.58) PTGS2HTR6ENPP2PSIP1ALDH1A1
Methylphenylsulfone SCHEMBL28288198 0.94 PTGS2 (0.58) PTGS2HTR6ENPP2PSIP1ALDH1A1
Methylphenylsulfone SCHEMBL28097901 0.94 PTGS2 (0.58) PTGS2HTR6ENPP2PSIP1ALDH1A1
Methylphenylsulfone SCHEMBL11698567 0.92 PTGS2 (0.56) PTGS2HTR6ENPP2PSIP1ALDH1A1
Methylphenylsulfone SCHEMBL27930437 0.92 PTGS2 (0.56) PTGS2HTR6ENPP2PSIP1ALDH1A1
Methylphenylsulfone SCHEMBL1925243 0.92 ALDH1A1 (0.59) PTGS2HTR6ENPP2PSIP1ALDH1A1
SCHEMBL17936671 0.89 HTR6 (0.70) PTGS2HTR6ENPP2ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7419 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122068093-A Lithium ion battery, preparation method thereof and electric equipment 宁德时代新能源科技股份有限公司 2026-05-19 CN claimed
US-20260049350-A1 HYBRIDIZATION COMPOSITIONS AND METHODS FOR MAKING AND USING COMPOSITIONS AGILENT TECHNOLOGIES INC (US) 2026-02-19 US claimed
US-12537221-B2 Electrolyte for secondary battery and secondary battery including the same DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2026-01-27 US claimed
EP-4674979-A2 HYBRIDIZATION COMPOSITIONS AND METHODS FOR MAKING AND USING COMPOSITIONS Agilent Technologies, Inc. (US) 2026-01-07 EP claimed
US-20250391919-A1 ELECTROLYTE SOLUTION, BATTERY CELL, BATTERY, AND POWER CONSUMING APPARATUS CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED (CN) 2025-12-25 US claimed
EP-4664591-A1 ELECTROLYTE SOLUTION, BATTERY CELL, BATTERY, AND ELECTRIC DEVICE Contemporary Amperex Technology Co., Limited (CN) 2025-12-17 EP claimed
EP-3959334-B1 HYBRIDIZATION COMPOSITIONS AND METHODS FOR MAKING AND USING COMPOSITIONS AGILENT TECHNOLOGIES INC (US) 2025-12-10 EP claimed
EP-4636890-A2 ELECTROLYTE COMPOSITIONS Faradion Limited (GB) 2025-10-22 EP claimed
US-20250277257-A1 HYBRIDIZATION COMPOSITIONS AND METHODS DAKO DENMARK APS (DK) 2025-09-04 US claimed
US-12404543-B2 Hybridization compositions and methods for making and using compositions AGILENT TECHNOLOGIES, INC. (US) 2025-09-02 US claimed
US-4198205-A SULFONIC ACID-FREE DISPERSE DYES BASF AKTIENGESELLSCHAFT (DE) 1980-04-15 US claimed
US-4122281-A DIURETIC, SALURETIC, ANTIHYPERTENSIVE BAYER AKTIENGESELLSCHAFT (DE) 1978-10-24 US claimed
US-4117145-A DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1978-09-26 US claimed
US-4117143-A USED AS ANTITHROMBOTIC AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1978-09-26 US claimed
US-4115566-A 7α Ureido cephem-4-carboxylic acid derivatives CIBA-GEIGY CORPORATION (US) 1978-09-19 US claimed
US-4008211-A Betainic azo dyestuffs containing cobalt in complex union with a colorless, tridentate ligand CIBA-GEIGY AG (CH) 1977-02-15 US claimed
US-3972888-A Process for the preparation of 1-hydroxy-pyridones HOECHST AKTIENGESELLSCHAFT (DT) 1976-08-03 US claimed
US-3969325-A Production of particulate BBB type polymer having an unusually high surface area CELANESE CORPORATION (US) 1976-07-13 US claimed
US-3956264-A Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component BAYER AKTIENGESELLSCHAFT (DT) 1976-05-11 US claimed
US-3933785-A Azo compounds CIBA-GEIGY AG (CH) 1976-01-20 US claimed