Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | XDH | P47989 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5502515 | 0.94 | ALDH1A1 (0.37) | ALDH1A1KMT2AKDM4EL3MBTL1MEN1 | |
| SCHEMBL5267628 | 0.80 | PPARD (0.39) | ALDH1A1KMT2AMEN1MAPTTDP1 | |
| SCHEMBL5506192 | 0.79 | MEN1 (0.37) | KMT2AMEN1MAPTTDP1CYP2C9 | |
| SCHEMBL5506161 | 0.77 | BRD4 (0.38) | KMT2AKDM4EL3MBTL1MEN1MAPT | |
| SCHEMBL5516043 | 0.76 | POLB (0.43) | ALDH1A1KMT2AKDM4EL3MBTL1MEN1 | |
| SCHEMBL5515208 | 0.74 | MAPT (0.38) | ALDH1A1KMT2AKDM4EL3MBTL1MEN1 | |
| SCHEMBL5517754 | 0.74 | POLB (0.36) | ALDH1A1KMT2AKDM4EL3MBTL1MEN1 | |
| SCHEMBL5270824 | 0.73 | PTPN1 (0.37) | ALDH1A1KMT2AKDM4EL3MBTL1MEN1 | |
| SCHEMBL5501123 | 0.73 | MAPT (0.37) | KMT2AL3MBTL1MEN1MAPTTDP1 | |
| SCHEMBL5506461 | 0.72 | ALOX5 (0.40) | ALDH1A1KMT2AL3MBTL1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |