Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRE | P78334 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5501123 | 0.94 | MAPT (0.37) | MEN1GABRPGABRDMAPTGABRA1 | |
| SCHEMBL5505357 | 0.86 | PDE10A (0.37) | MAPTTDP1 | |
| SCHEMBL5267628 | 0.81 | PPARD (0.39) | MEN1GABRPGABRDMAPTGABRA1 | |
| SCHEMBL5501141 | 0.79 | ALDH1A1 (0.37) | MEN1GABRPGABRDMAPTGABRA1 | |
| SCHEMBL5506161 | 0.79 | BRD4 (0.38) | MEN1GABRPGABRDMAPTGABRA1 | |
| SCHEMBL5516043 | 0.76 | POLB (0.43) | MEN1GABRPGABRDMAPTGABRA1 | |
| SCHEMBL5270824 | 0.75 | PTPN1 (0.37) | MEN1GABRPGABRDMAPTGABRA1 | |
| SCHEMBL5515208 | 0.74 | MAPT (0.38) | MEN1GABRPGABRDMAPTGABRA1 | |
| SCHEMBL5517754 | 0.74 | POLB (0.36) | MEN1GABRPGABRDMAPTGABRA1 | |
| SCHEMBL5506461 | 0.73 | ALOX5 (0.40) | MEN1GABRPGABRDMAPTGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |