Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTA1 | P08263 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA7 | P43166 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7551903 | 0.82 | CA12 (0.59) | GSTA1CA12CA1CA2CA7 | |
| SCHEMBL3135339 | 0.82 | FOLH1 (0.41) | GSTA1CYP1A2ALOX15CYP2C19CYP2C9 | |
| SCHEMBL7713693 | 0.81 | GSTA1 (0.67) | GSTA1CA12CA1CA2CA7 | |
| SCHEMBL3905124 | 0.78 | CA12 (0.70) | GSTA1CA12CA1CA2CA7 | |
| SCHEMBL11691699 | 0.76 | CA12 (0.68) | GSTA1CA12CA1CA2CA7 | |
| SCHEMBL11843932 | 0.75 | RECQL (0.51) | GSTA1CA12CA1CA2CA7 | |
| SCHEMBL2280625 | 0.74 | ALDH1A1 (0.42) | HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL8861157 | 0.73 | CA12 (0.52) | GSTA1CA12CA1CA2CA7 | |
| SCHEMBL4440969 | 0.72 | CES2 (0.39) | HPGDLMNAALDH1A1MEN1MAPT | |
| SCHEMBL4441884 | 0.72 | RECQL (0.49) | CA1CA2HPGDCYP1A2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761259-A2 | TOPICAL FORMULATIONS FOR TREATING ALLERGIC DISEASES | ALCON INC. (CH) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006004757-A2 | TOPICAL FORMULATIONS FOR TREATING ALLERGIC DISEASES | ALCON, INC. (CH) | 2006-01-12 | — | — | WO | disclosed |
| US-20050288283-A1 | Topical formulations for treating allergic diseases | ALCON, INC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288283-A1 | Topical formulations for treating allergic diseases | TSLP, HRH2, HRH1 | GSTA1 2956/4885CA12 1010/4885CA1 2888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.