Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5506950 | 0.79 | CHEK1 (0.50) | CHEK1AURKADAPK3JAK2PRKD3 | |
| SCHEMBL5505355 | 0.73 | CYP19A1 (0.43) | CHEK1AURKADAPK3JAK2PRKD3 | |
| SCHEMBL5998058 | 0.65 | ATAD2 (0.45) | ATAD2KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL5503465 | 0.64 | ATAD2 (0.44) | ATAD2KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL16376952 | 0.60 | AADAT (0.36) | KDM4EMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL19702960 | 0.57 | HSD17B10 (0.42) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL31469987 | 0.57 | CHEK1 (0.47) | CHEK1AURKADAPK3JAK2PRKD3 | |
| SCHEMBL6765366 | 0.57 | CHEK1 (0.44) | CHEK1AURKADAPK3JAK2PRKD3 | |
| SCHEMBL3424164 | 0.54 | ALDH1A1 (0.68) | CA12CA1CA9ATAD2KDM4E | |
| SCHEMBL30032581 | 0.54 | ALDH1A1 (0.68) | CA12CA1CA9ATAD2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781642-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006016221-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |