Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257607 | 0.80 | ALDH1A1 (0.47) | HDAC1HDAC2LTB4RPPARDRECQL | |
| SCHEMBL9261099 | 0.79 | LMNA (0.53) | LTB4RPPARDKDM4E | |
| SCHEMBL9260900 | 0.79 | LTB4R (0.45) | HDAC1HDAC2LTB4RPPARD | |
| SCHEMBL5504598 | 0.78 | LTB4R (0.42) | HDAC1HDAC2LTB4RPPARDMCL1 | |
| SCHEMBL4901701 | 0.77 | PRMT6 (0.43) | LTB4RPPARDKDM4E | |
| SCHEMBL9258896 | 0.77 | LTB4R (0.41) | HDAC1HDAC2LTB4RPPARDMCL1 | |
| SCHEMBL9255816 | 0.77 | LTB4R (0.43) | HDAC1HDAC2LTB4RPPARD | |
| SCHEMBL9258901 | 0.77 | LTB4R (0.41) | HDAC1HDAC2LTB4RPPARDMCL1 | |
| SCHEMBL3863779 | 0.76 | MTNR1A (0.44) | L3MBTL1PPARDRECQLMTNR1AMTNR1B | |
| SCHEMBL14642800 | 0.76 | TAAR1 (0.46) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807439-A2 | KETOLIDE DERIVATIVES AS ANTIBACTERIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006046112-A2 | KETOLIDE DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-05-04 | — | — | WO | disclosed |