Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258896 | 1.00 | LTB4R (0.41) | LTB4RPPARDHDAC1HDAC2HDAC8 | |
| SCHEMBL9254793 | 0.84 | PRMT6 (0.39) | LTB4RPPARDHDAC1HDAC2HDAC8 | |
| SCHEMBL9254796 | 0.84 | PRMT6 (0.39) | LTB4RPPARDHDAC1HDAC2HDAC8 | |
| SCHEMBL9259547 | 0.82 | PRMT6 (0.44) | LTB4RPPARDHDAC1HDAC2HDAC8 | |
| SCHEMBL9257607 | 0.79 | ALDH1A1 (0.47) | LTB4RPPARDHDAC1HDAC2ALDH1A1 | |
| SCHEMBL9254689 | 0.78 | PRMT6 (0.40) | LTB4RPPARDHDAC1HDAC2ALDH1A1 | |
| SCHEMBL9261099 | 0.78 | LMNA (0.53) | LTB4RPPARDKDM4EALDH1A1RXRA | |
| SCHEMBL9260900 | 0.78 | LTB4R (0.45) | LTB4RPPARDHDAC1HDAC2SLC6A9 | |
| SCHEMBL5504598 | 0.77 | LTB4R (0.42) | LTB4RPPARDHDAC1HDAC2ACMSD | |
| SCHEMBL5504603 | 0.77 | HDAC1 (0.45) | LTB4RPPARDHDAC1HDAC2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439932-A | Anticholesterol agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5306728-A | Substituted amine derivatives having antihyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0448078-A2 | Substituted amine derivatives having anti-hyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |