Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5511211 | 0.81 | — | — | |
| SCHEMBL5501428 | 0.74 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL5505355 | 0.74 | CYP19A1 (0.43) | CYP19A1CNR2CNR1 | |
| SCHEMBL5001377 | 0.70 | CYP19A1 (0.38) | CYP19A1PGR | |
| SCHEMBL5505340 | 0.69 | CYP19A1 (0.37) | CYP19A1PGR | |
| SCHEMBL18571340 | 0.67 | HTT (0.34) | CYP19A1 | |
| SCHEMBL18571099 | 0.61 | ALDH1A1 (0.35) | CYP19A1PGR | |
| SCHEMBL22540651 | 0.61 | — | — | |
| SCHEMBL4997606 | 0.60 | ATAD2 (0.44) | CYP19A1 | |
| SCHEMBL22540652 | 0.59 | PGR (0.31) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781643-A1 | OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006016220-A1 | OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |