⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505345 | 0.81 | CYP19A1 (0.36) | — | |
| SCHEMBL5501428 | 0.80 | CYP19A1 (0.31) | — | |
| SCHEMBL5506950 | 0.70 | CHEK1 (0.50) | — | |
| SCHEMBL5004930 | 0.65 | BMPR1B (0.42) | — | |
| SCHEMBL5511206 | 0.63 | BMPR1B (0.41) | — | |
| SCHEMBL3035796 | 0.62 | SRD5A1 (0.39) | — | |
| SCHEMBL3826017 | 0.61 | MAPT (0.37) | — | |
| SCHEMBL6530748 | 0.60 | CYP11B2 (0.34) | — | |
| SCHEMBL18571340 | 0.60 | HTT (0.34) | — | |
| SCHEMBL23008844 | 0.58 | RIPK1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781642-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006016221-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |