Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5507776 | 0.91 | RXRA (0.42) | PPARDTHRBFFAR1PPARA | |
| SCHEMBL5507450 | 0.90 | PTGDR2 (0.40) | PPARDTHRBFFAR1SLC6A2SLC6A4 | |
| SCHEMBL5505765 | 0.90 | PTGDR2 (0.44) | PPARDTHRBSCN8ASCN10AFFAR1 | |
| SCHEMBL5502236 | 0.88 | FFAR1 (0.38) | PPARDTHRBFFAR1PTGDR2PPARA | |
| SCHEMBL5506365 | 0.86 | LGALS8 (0.41) | PPARDTHRBTRPV1FFAR1PTGDR2 | |
| SCHEMBL5505100 | 0.84 | THRA (0.41) | PPARDTHRBTRPV1FFAR1PTGDR2 | |
| SCHEMBL5510893 | 0.83 | PPARD (0.39) | PPARDSCN8ASCN10ASLC6A2SLC6A4 | |
| SCHEMBL5267628 | 0.81 | PPARD (0.39) | PPARDFFAR1PPARA | |
| SCHEMBL5502243 | 0.80 | GCK (0.40) | PPARDTHRBPTGDR2 | |
| SCHEMBL5517204 | 0.79 | TOP1 (0.34) | PPARDSCN8ASCN10APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |