SCHEMBL550615

SCHEMBL550615

CO[Si](CCCN=C=S)(OC)OC

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 3/20 0.45
TRPA1 O75762 8/20 0.43
MIF P14174 5/20 0.40
KEAP1 Q14145 2/20 0.39
NFE2L2 Q16236 2/20 0.39
LMNA P02545 2/20 0.39
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39
BACH1 O14867 1/20 0.39
MAFK O60675 1/20 0.39
EGFR P00533 1/20 0.39
PTGS2 P35354 1/20 0.39
GSK3B P49841 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3835195 0.94 NAAA (0.48) NAAATRPA1MIFKEAP1NFE2L2
SCHEMBL2772741 0.88 TRPA1 (0.39) NAAATRPA1MIFKEAP1NFE2L2
SCHEMBL2772743 0.82 NAAA (0.33) NAAATRPA1
SCHEMBL8675289 0.82 LMNA (0.35) LMNA
SCHEMBL6058459 0.81 ALDH1A1 (0.37) NAAATRPA1ALDH1A1
SCHEMBL551245 0.81 TRPA1 (0.47) NAAATRPA1MIFKEAP1NFE2L2
SCHEMBL551639 0.79 NAAA (0.47) NAAATRPA1MIFKEAP1NFE2L2
SCHEMBL49581 0.78 LMNA (0.33) LMNA
SCHEMBL29225704 0.78 LMNA (0.33) LMNA
SCHEMBL31505966 0.77 LMNA (0.32) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024216910-A1 HIGH-CHEMICAL-RESISTANCE POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, PREPARATION METHOD THEREFOR, AND USE THEREOF 明士(北京)新材料开发有限公司 2024-10-24 WO claimed
US-20140234579-A1 Composite Preventing Ice Adhesion WANG LIANG (US) 2014-08-21 US claimed
US-8642704-B2 Hysteresis elastomeric compositions comprising polymers terminated with isocyanato alkoxysilanes BRIDGESTONE CORPORATION (JP) 2014-02-04 US claimed
EP-1631595-B1 IMPROVED HYSTERESIS ELASTOMERIC COMPOSITIONS COMPRISING POLYMERS TERMINATED WITH ISOCYANATO ALKOXYSILANES BRIDGESTONE CORP (JP) 2013-08-28 EP claimed
EP-1631596-B1 IMPROVED HYSTERESIS ELASTOMERIC COMPOSITIONS COMPRISING SEQUENTIALLY TERMINATED POLYMERS BRIDGESTONE CORP (JP) 2013-08-14 EP claimed
EP-1412413-B1 SYNTHESIS AND USE OF ORGANOSILICA PARTICLES NANOMICS BIOSYSTEMS PTY LTD (AU) 2011-08-10 EP claimed
US-20100234534-A1 HYSTERESIS ELASTOMERIC COMPOSITIONS COMPRISING POLYMERS TERMINATED WITH ISOCYANATO ALKOXYSILANES BRIDGESTONE CORPORATION (JP) 2010-09-16 US claimed
EP-1448694-B1 CURABLE ORGANIC RESIN COMPOSITION DOW CORNING TORAY CO LTD (JP) 2009-10-07 EP claimed
US-7534839-B2 Sequentially terminated elastomers BRIDGESTONE CORPORATION (JP) 2009-05-19 US claimed
US-7446137-B2 Thermosetting resin and thiocyanato-containing organohydrocarbonoxysilane DOW CORNING TORAY SILICONE CO., LTD. (JP) 2008-11-04 US claimed
WO-2004111093-A1 IMPROVED HYSTERESIS ELASTOMERIC COMPOSITIONS COMPRISING POLYMERS TERMINATED WITH ISOCYANATO ALKOXYSILANES BRIDGESTONE CORPORATION (JP) 2004-12-23 WO claimed
US-20040249090-A1 Thermosetting organic resin composition DOW TORAY CO., LTD. (JP) 2004-12-09 US claimed
WO-2003002633-A9 SYNTHESIS AND USE OF ORGANOSILICA PARTICLES NANOMICS BIOSYSTEMS PTY LTD (AU) 2004-08-26 WO claimed
EP-1448694-A1 CURABLE ORGANIC RESIN COMPOSITION Dow Corning Toray Silicone Co., Ltd. (JP) 2004-08-25 EP claimed
EP-1412413-A1 SYNTHESIS AND USE OF ORGANOSILICA PARTICLES Nanomics Biosystems Pty, Ltd. (AU) 2004-04-28 EP claimed
US-20040000524-A1 Device and method of use for aldehyde removal ZHU PETER (US) 2004-01-01 US claimed
US-20030124564-A1 Synthesis and use of organosilica particles NANOMICS BIOSYSTEMS PTY LTD (AU) 2003-07-03 US claimed
WO-2003037976-A1 CURABLE ORGANIC RESIN COMPOSITION DOW CORNING TORAY SILICONE CO., LTD. (JP) 2003-05-08 WO claimed
WO-2003002633-A1 SYNTHESIS AND USE OF ORGANOSILICA PARTICLES NANOMICS BIOSYSTEMS PTY, LTD. (AU) 2003-01-09 WO claimed
US-20020117449-A1 Device and method of use for aldehyde removal ETHICON, INC. 2002-08-29 US claimed