SCHEMBL6058459

SCHEMBL6058459

CO[Si](CCCN=C=S)(OC)OC.ClCC1CO1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
NAAA Q02083 1/20 0.32
TRPA1 O75762 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL550615 0.81 NAAA (0.45) ALDH1A1NAAATRPA1
SCHEMBL3835195 0.76 NAAA (0.48) ALDH1A1NAAATRPA1
SCHEMBL2772741 0.74 TRPA1 (0.39) ALDH1A1NAAATRPA1
SCHEMBL551245 0.69 TRPA1 (0.47) ALDH1A1NAAATRPA1
SCHEMBL9860608 0.69 TSHR (0.44) ALDH1A1TDP1
SCHEMBL3478667 0.67 ALDH1A1 (0.45) ALDH1A1TDP1
SCHEMBL2772743 0.67 NAAA (0.33) NAAATRPA1
SCHEMBL8675289 0.66 LMNA (0.35)
SCHEMBL5402269 0.66 ALDH1A1 (0.37) ALDH1A1TDP1TRPA1
SCHEMBL238324 0.66 ALDH1A1 (0.48) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060135701-A1 Hysteresis elastomeric compositions comprising sequentially terminated polymers BRIDGESTONE CORPORATION (JP) 2006-06-22 US claimed
EP-1631596-B1 IMPROVED HYSTERESIS ELASTOMERIC COMPOSITIONS COMPRISING SEQUENTIALLY TERMINATED POLYMERS BRIDGESTONE CORP (JP) 2013-08-14 EP disclosed