SCHEMBL550742

SCHEMBL550742

Cc1cc(I)ccc1N(C(=O)O)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.33
LMNA P02545 1/20 0.33
TPMT P51580 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7412461 0.83 KDM4E (0.41) LMNA
SCHEMBL8801278 0.80 ALDH1A1 (0.43)
SCHEMBL8802370 0.80 HSD17B1 (0.39) LMNA
SCHEMBL2191688 0.80 RAB9A (0.37) LMNA
SCHEMBL7412320 0.78 HTT (0.43) LMNA
SCHEMBL6005339 0.75 TRPM8 (0.46) LMNA
SCHEMBL19534969 0.75 HSD11B1 (0.40)
SCHEMBL17645554 0.73 TPMT (0.40) TPMT
SCHEMBL2432062 0.72 FSCN1 (0.39)
SCHEMBL11768389 0.71 LMNA (0.36) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110689-B2 Benzanilides with insecticidal activity BAYER CROPSCIENE AG (DE) 2012-02-07 US disclosed