SCHEMBL5508095

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5505713	0.99	ALDH1A1 (0.40)	ALDH1A1SMN1; SMN2HTTTSHRNPSR1
	SCHEMBL5504699	0.91	ALDH1A1 (0.44)	ALDH1A1SMN1; SMN2HTTTSHRNPSR1
	SCHEMBL8268445	0.87	ALOX5 (0.33)	ALDH1A1SMN1; SMN2HTTTSHRNPSR1
	SCHEMBL8267961	0.82	ALOX5 (0.34)	ALDH1A1SMN1; SMN2HTTTSHRNPSR1
	SCHEMBL8267973	0.82	ALDH1A1 (0.36)	ALDH1A1SMN1; SMN2HTTTSHRNPSR1
	SCHEMBL5508079	0.80	CCR2 (0.41)	NR1H4ALOX5RARARARGMAPT
	SCHEMBL5508253	0.78	ALOX5 (0.60)	SMN1; SMN2HTTNR1H4ALOX5RARA
	SCHEMBL5508964	0.77	ALOX5 (0.45)	NR1H4ALOX5RARARARGLMNA
	SCHEMBL5505018	0.77	ALOX5 (0.51)	ALDH1A1SMN1; SMN2ALOX5MAPTLMNA
	SCHEMBL5508180	0.76	NPC1 (0.44)	ALDH1A1SMN1; SMN2HTTNPSR1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.