SCHEMBL5508964

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8267431	0.87	ALOX5 (0.39)	ALOX5USP2RARARARGRARB
	SCHEMBL5508253	0.82	ALOX5 (0.60)	ALOX5RARARARGRARBNR1H4
	SCHEMBL5508079	0.82	CCR2 (0.41)	ALOX5RARARARGRARBNR1H4
	SCHEMBL5508180	0.80	NPC1 (0.44)	ALOX5RARARARGRARBMEN1
	SCHEMBL5505018	0.79	ALOX5 (0.51)	ALOX5MEN1KMT2ARAB9ALMNA
	SCHEMBL5508095	0.77	ALDH1A1 (0.40)	ALOX5RARARARGRARBNR1H4
	SCHEMBL5505713	0.76	ALDH1A1 (0.40)	ALOX5RARARARGRARBNR1H4
	SCHEMBL5504699	0.76	ALDH1A1 (0.44)	ALOX5RARARARGNR1H4MEN1
	SCHEMBL5510418	0.74	RARA (0.39)	ALOX5RARARARGRARBNR1H4
	SCHEMBL5510736	0.73	RARA (0.39)	ALOX5RARARARGRARBNR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.