Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5519001 | 1.00 | ADRB1 (0.37) | ADRB1HSD11B1 | |
| SCHEMBL5518718 | 0.85 | IRAK4 (0.34) | ADRB1 | |
| SCHEMBL16402620 | 0.84 | ADRB1 (0.43) | ADRB1HSD11B1 | |
| SCHEMBL15830965 | 0.77 | ADRB1 (0.44) | ADRB1HSD11B1 | |
| SCHEMBL5313456 | 0.74 | CYP3A4 (0.48) | — | |
| SCHEMBL19582874 | 0.74 | HTR7 (0.32) | — | |
| SCHEMBL6179382 | 0.74 | NOS3 (0.38) | — | |
| SCHEMBL4715740 | 0.74 | CCR1 (0.32) | — | |
| SCHEMBL4760290 | 0.73 | ALDH1A1 (0.35) | — | |
| SCHEMBL13184023 | 0.72 | ADRB1 (0.58) | ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213338-A1 | Triazolo-Pyridazine Compounds and Derivatives Thereof Useful in the Treatment of Neuropathic Pain | MERCK & CO., INC. | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213338-A1 | Triazolo-Pyridazine Compounds and Derivatives Thereof Useful in the Treatment of Neuropathic Pain | PER2, CNR2, OPRD1 | ADRB1 192/4885HSD11B1 1991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.