Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435032 | 0.90 | MTNR1A (0.38) | F2ELANEMTNR1AMTNR1B | |
| SCHEMBL9727664 | 0.90 | MAPK1 (0.38) | MAOAMAOBMTNR1AMTNR1B | |
| SCHEMBL14435047 | 0.89 | F2 (0.39) | F2ELANE | |
| SCHEMBL9727458 | 0.86 | PTGER1 (0.47) | — | |
| SCHEMBL5506271 | 0.86 | MAOA (0.41) | FFAR1MAOAMAOB | |
| SCHEMBL27739159 | 0.84 | MAOB (0.41) | MAOAMAOB | |
| SCHEMBL9727691 | 0.83 | MTNR1B (0.42) | MTNR1B | |
| SCHEMBL9727339 | 0.80 | MAOB (0.43) | MAOAMAOB | |
| SCHEMBL9727767 | 0.80 | HIF1A (0.36) | PPARGMTNR1AMTNR1B | |
| SCHEMBL9727765 | 0.80 | MTNR1B (0.39) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070202547-A1 | Methods For Detecting Substances Which Bind To The Amyloid Precursor Protein Or Beta Amyloid Fragments, And Binding Compounds | MERCK & CO., INC. | 2007-08-30 | — | — | US | disclosed |
| US-20070202547-A1 | Methods For Detecting Substances Which Bind To The Amyloid Precursor Protein Or Beta Amyloid Fragments, And Binding Compounds | MERCK & CO., INC. | 2007-08-30 | — | — | US | disclosed |
| US-20070202547-A1 | Methods For Detecting Substances Which Bind To The Amyloid Precursor Protein Or Beta Amyloid Fragments, And Binding Compounds | MERCK & CO., INC. | 2007-08-30 | — | — | US | disclosed |
| US-5091533-A | Treating allergies, cardiovascular disorders, inflammation | MERCK FROSST CANADA, INC. (CA) | 1992-02-25 | — | — | US | disclosed |
| EP-0447189-A1 | 5-Hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors | MERCK FROSST CANADA INC. (CA) | 1991-09-18 | — | — | EP | disclosed |