Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 17/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5520458 | 1.00 | FAAH (0.43) | FAAHCES1CTSSCYP3A4CYP2C9 | |
| SCHEMBL5517452 | 0.94 | FAAH (0.46) | FAAHCES1CTSSCYP3A4CYP2C9 | |
| SCHEMBL5519481 | 0.92 | CTSS (0.48) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL5517725 | 0.92 | CTSS (0.48) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL6048146 | 0.82 | CTSS (0.50) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL27663433 | 0.81 | CTSS (0.50) | FAAHCES1CTSSCYP3A4CYP2C9 | |
| SCHEMBL5800404 | 0.79 | CTSS (0.43) | FAAHCES1CTSSCYP3A4CYP2C9 | |
| SCHEMBL5526908 | 0.79 | HDAC3 (0.40) | — | |
| SCHEMBL14378279 | 0.78 | FAAH (0.49) | FAAHCES1CTSSCYP3A4CYP2C9 | |
| SCHEMBL5520457 | 0.78 | TP53 (0.40) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070088001-A1 | Silinane compounds as cysteine protease inhibitors | QUEST DIAGNOSTICS INVESTMENTS LLC | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088001-A1 | Silinane compounds as cysteine protease inhibitors | CTSV, CTSB, CTSS | FAAH 1228/4885CES1 476/4885CTSS 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.