SCHEMBL5520150

SCHEMBL5520150

Cc1nc2cc(NC(=O)OCC3CCCCC3)ccc2o1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.53
NPC1 O15118 5/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
STAT1 P42224 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
LMNA P02545 3/20 0.52
KDM4E B2RXH2 4/20 0.51
MAPT P10636 3/20 0.51
MEN1 O00255 2/20 0.51
POLB P06746 2/20 0.51
KMT2A Q03164 2/20 0.51
ALDH1A1 P00352 3/20 0.49
MGLL Q99685 2/20 0.48
HTT P42858 1/20 0.48
EPHX2 P34913 1/20 0.48
TP53 P04637 2/20 0.47
MAPK1 P28482 2/20 0.47
GAA P10253 2/20 0.45
AGPAT2 O15120 1/20 0.45
PKM P14618 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5524308 0.91 POLB (0.54) RAB9ANPC1SMN1; SMN2STAT1L3MBTL1
SCHEMBL4962140 0.83 RAB9A (0.56) RAB9ANPC1SMN1; SMN2STAT1L3MBTL1
SCHEMBL4968463 0.82 RAB9A (0.62) RAB9ANPC1SMN1; SMN2STAT1L3MBTL1
SCHEMBL4969328 0.78 RAB9A (0.55) RAB9ANPC1SMN1; SMN2LMNAKDM4E
SCHEMBL5523279 0.77 RAB9A (0.64) RAB9ANPC1SMN1; SMN2STAT1L3MBTL1
SCHEMBL5526482 0.76 RAB9A (0.67) RAB9ANPC1SMN1; SMN2LMNAKDM4E
SCHEMBL14470501 0.76 RAB9A (0.66) RAB9ANPC1SMN1; SMN2STAT1L3MBTL1
SCHEMBL4963936 0.76 MGLL (0.53) NPC1MAPTMEN1POLBKMT2A
SCHEMBL17346753 0.76 MGLL (0.55) RAB9ANPC1SMN1; SMN2L3MBTL1LMNA
SCHEMBL5520154 0.75 RAB9A (0.45) RAB9ANPC1SMN1; SMN2STAT1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070155747-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE KADMUS PHARMACEUTICALS, INC. (US) 2007-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070155747-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE FAAH, FAAH2, ABHD6 RAB9A 2202/4885NPC1 588/4885SMN1; SMN2 4547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.