SCHEMBL5526482

SCHEMBL5526482

Cc1nc2ccc(NC(=O)OCC3CCCCC3)cc2s1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.67
NPC1 O15118 5/20 0.67
SMN1; SMN2 Q16637 7/20 0.56
HSD17B10 Q99714 1/20 0.56
LDHA P00338 2/20 0.56
MAPT P10636 6/20 0.56
CASP3 P42574 1/20 0.56
SENP8 Q96LD8 1/20 0.56
SENP7 Q9BQF6 1/20 0.56
SENP6 Q9GZR1 1/20 0.56
KDM4E B2RXH2 3/20 0.54
ALDH1A1 P00352 2/20 0.54
TSHR P16473 2/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
PDE4B Q07343 1/20 0.53
GAA P10253 2/20 0.52
POLB P06746 1/20 0.52
HTT P42858 1/20 0.51
LMNA P02545 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4969328 0.91 RAB9A (0.55) RAB9ANPC1SMN1; SMN2HSD17B10LDHA
SCHEMBL4968596 0.83 RAB9A (0.61) RAB9ANPC1SMN1; SMN2HSD17B10LDHA
SCHEMBL14079746 0.82 LDHA (0.68) RAB9ANPC1SMN1; SMN2LDHAMAPT
SCHEMBL14470411 0.81 RAB9A (0.68) RAB9ANPC1SMN1; SMN2HSD17B10LDHA
SCHEMBL4499693 0.79 EPHX2 (0.56) RAB9ANPC1SMN1; SMN2LDHAMAPT
SCHEMBL5524308 0.78 POLB (0.54) RAB9ANPC1SMN1; SMN2MAPTCASP3
SCHEMBL14470416 0.77 EPHX2 (0.75) RAB9ANPC1SMN1; SMN2HSD17B10LDHA
SCHEMBL5520150 0.76 RAB9A (0.53) RAB9ANPC1SMN1; SMN2HSD17B10MAPT
SCHEMBL4964208 0.76 NPC1 (0.55) RAB9ANPC1SMN1; SMN2HSD17B10MAPT
SCHEMBL17346753 0.76 MGLL (0.55) RAB9ANPC1SMN1; SMN2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070155747-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE KADMUS PHARMACEUTICALS, INC. (US) 2007-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070155747-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE FAAH, FAAH2, ABHD6 RAB9A 2202/4885NPC1 588/4885SMN1; SMN2 4547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.