Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609929 | 0.81 | MEN1 (0.43) | MEN1KMT2ALMNACYP2D6HRH1 | |
| SCHEMBL4889259 | 0.78 | KEAP1 (0.51) | CYP2D6HRH1KEAP1NFE2L2MAPT | |
| SCHEMBL6589615 | 0.78 | KEAP1 (0.47) | MEN1KMT2ALMNACYP2D6HRH1 | |
| SCHEMBL9193099 | 0.77 | MAPT (0.52) | CYP2D6HRH1KEAP1NFE2L2MAPT | |
| SCHEMBL22461931 | 0.69 | CYP2D6 (0.50) | MEN1KMT2ALMNACYP2D6HRH1 | |
| SCHEMBL6860669 | 0.68 | MEN1 (0.31) | MEN1KMT2ALMNACYP2D6HRH1 | |
| SCHEMBL6854478 | 0.68 | MEN1 (0.31) | MEN1KMT2ALMNACYP2D6HRH1 | |
| SCHEMBL28956828 | 0.65 | ALDH1A1 (0.35) | KMT2AMAPTALDH1A1 | |
| SCHEMBL15283226 | 0.65 | LMNA (0.63) | MEN1KMT2ALMNAMAPTNPSR1 | |
| SCHEMBL3316886 | 0.62 | LMNA (0.45) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110695-B2 | Compounds and compositions containing silicon and/or other heteroatoms and/or metals and methods of making and using them | WELKER MARK E (US) | 2012-02-07 | — | — | US | disclosed |
| US-20100056801-A1 | Compounds And Compositions Containing Silicon And/Or Other Heteroatoms And/Or Metals And Methods of Making And Using Them | WELKER MARK E | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056801-A1 | Compounds And Compositions Containing Silicon And/Or Other Heteroatoms And/Or Metals And Methods of Making And Using Them | CA6, SOD1, CA1 | MEN1 27/4885KMT2A 1805/4885LMNA 1005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.