SCHEMBL5524316

SCHEMBL5524316

Cc1nc2ccc(OC(=O)NCC3CCCCC3)cc2o1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP13 P45452 1/20 0.44
FAAH O00519 1/20 0.43
BCHE P06276 1/20 0.43
ACHE P22303 1/20 0.43
POLB P06746 2/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
MAOB P27338 1/20 0.40
CHRNA7 P36544 1/20 0.40
F2RL3 Q96RI0 1/20 0.40
F2 P00734 1/20 0.40
PLG P00747 1/20 0.40
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
PRSS3 P35030 1/20 0.40
ST14 Q9Y5Y6 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPC1 O15118 1/20 0.40
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14470490 0.94 POLB (0.43) POLBCHRNA7SMN1; SMN2TAS1R3TAS1R1
SCHEMBL5520154 0.91 RAB9A (0.45) MMP13FAAHBCHEACHEPOLB
SCHEMBL14470498 0.85 RAB9A (0.47) POLBMEN1KMT2ACHRNA7SMN1; SMN2
SCHEMBL5517906 0.84 FAAH (0.57) FAAH
SCHEMBL14470495 0.79 TAS1R3 (0.48) FAAHPOLBKMT2AMAOBSMN1; SMN2
SCHEMBL5526489 0.79 RAB9A (0.53) MMP13MEN1KMT2AMAOBSMN1; SMN2
SCHEMBL14470401 0.79 POLB (0.62) POLBMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL4969338 0.77 CNR1 (0.47) MMP13FAAHBCHEACHEPOLB
SCHEMBL4964213 0.76 ALDH1A1 (0.59) FAAHSMN1; SMN2NPC1
SCHEMBL14470481 0.76 EPHX1 (0.65) FAAHBCHEACHEPOLBF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070155747-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE KADMUS PHARMACEUTICALS, INC. (US) 2007-07-05 US disclosed
US-20070155747-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE KADMUS PHARMACEUTICALS, INC. (US) 2007-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070155747-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE FAAH, FAAH2, ABHD6 MMP13 1253/4885FAAH 1/4885BCHE 138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.