SCHEMBL5524749

SCHEMBL5524749

COCc1cc(C(C)=O)cc(C2CCCCC2)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
MAPT P10636 3/20 0.39
KDM4E B2RXH2 1/20 0.39
PRKCE Q02156 2/20 0.38
LMNA P02545 1/20 0.37
PTGDR2 Q9Y5Y4 5/20 0.36
PTGDR Q13258 2/20 0.36
CA5A P35218 1/20 0.35
P2RX3 P56373 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
ALDH1A1 P00352 2/20 0.34
GAA P10253 1/20 0.34
CNR1 P21554 3/20 0.33
CNR2 P34972 3/20 0.33
PRKCG P05129 1/20 0.33
PRKCA P17252 1/20 0.33
APEX1 P27695 1/20 0.33
RECQL P46063 1/20 0.33
MYLK Q15746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16850508 0.83 NUDT1 (0.39) MEN1KMT2AMAPTKDM4EPRKCE
SCHEMBL19600589 0.78 NUDT1 (0.39) MEN1KMT2AMAPTKDM4EPRKCE
SCHEMBL18221714 0.78 PRKCE (0.35) MEN1KMT2AMAPTKDM4EPRKCE
SCHEMBL18220626 0.76 MEN1 (0.35) MEN1KMT2AMAPTKDM4EPRKCE
SCHEMBL5527123 0.76 PRKCE (0.41) MEN1KMT2AMAPTKDM4EPRKCE
SCHEMBL16318058 0.76 P2RX3 (0.35) MEN1KMT2AMAPTKDM4EPRKCE
SCHEMBL18101030 0.75 ACHE (0.45) MEN1KMT2AMAPTKDM4EPRKCE
SCHEMBL3809998 0.74 KDM4E (0.42) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL9189273 0.73 NUDT1 (0.43) MEN1KMT2AMAPTKDM4EPRKCE
SCHEMBL16850510 0.73 ALDH1A1 (0.41) MEN1KMT2AMAPTKDM4EPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8173349-B2 Photosensitive resin composition, polymer compound, method of forming a pattern, and electronic device FUJIFILM CORPORATION (JP) 2012-05-08 US disclosed
US-7977028-B2 Photosensitive resin composition and adhesion promoter TORAY INDUSTRIES, INC. (JP) 2011-07-12 US disclosed
US-20100080963-A1 PHOTOSENSITIVE RESIN COMPOSITION, POLYMER COMPOUND, METHOD OF FORMING A PATTERN, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-7615324-B2 Photosensitive composition, and cured relief pattern production method and semiconductor device using the same FUJIFILM CORPORATION (JP) 2009-11-10 US disclosed
US-7598009-B2 Photosensitive resin composition, production method for cured relief pattern using it, and semiconductor device FUJIFILM CORPORATION (JP) 2009-10-06 US disclosed
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER TORAY INDUSTRIES, INC. (JP) 2009-05-14 US disclosed
US-7507518-B2 Photosensitive resin precursor composition TORAY INDUSTRIES, INC. (JP) 2009-03-24 US disclosed
US-20090035693-A1 PHOTOSENSITIVE RESIN COMPOSITION, PRODUCTION METHOD FOR CURED RELIEF PATTERN USING IT, AND SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2009-02-05 US disclosed
US-20080227024-A1 PHOTOSENSITIVE COMPOSITION, AND CURED RELIEF PATTERN PRODUCTION METHOD AND SEMICONDUCTOR DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2008-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER PCNA, TERB1, SMC2 MEN1 4387/4885KMT2A 56/4885MAPT 1072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.