SCHEMBL5527391

SCHEMBL5527391

Cc1cc(O)c(-c2c(C)ccc(O)c2-c2cc(C3CCCCC3)c(C)cc2O)cc1C1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NUDT1 P36639 1/20 0.42
▸ BACE1 P56817 1/20 0.42
▸ HSP90AA1 P07900 1/20 0.39
▸ ACMSD Q8TDX5 2/20 0.35
▸ KDM4E B2RXH2 2/20 0.33
▸ MAPT P10636 2/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ THRB P10828 2/20 0.33
▸ PTGDR2 Q9Y5Y4 1/20 0.33
▸ PSMB5 P28074 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.32
▸ CYP1A2 P05177 1/20 0.32
▸ CYP3A4 P08684 1/20 0.32
▸ CYP2D6 P10635 1/20 0.32
▸ G6PD P11413 1/20 0.32
▸ CYP2C9 P11712 1/20 0.32
▸ PKM P14618 1/20 0.32
▸ HPGD P15428 1/20 0.32
▸ ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3787886 0.90 NUDT1 (0.44) NUDT1BACE1HSP90AA1ACMSDKDM4E
SCHEMBL9136538 0.84 NUDT1 (0.40) NUDT1BACE1HSP90AA1ACMSDKDM4E
SCHEMBL5526208 0.82 ELANE (0.35) NUDT1BACE1HSP90AA1ACMSDKDM4E
SCHEMBL8897907 0.82 ACMSD (0.48) NUDT1BACE1ACMSDKDM4EKMT2A
Ethane SCHEMBL28868993 0.81 NUDT1 (0.37) NUDT1BACE1HSP90AA1ACMSDKDM4E
SCHEMBL7522760 0.79 HSP90AA1 (0.38) NUDT1BACE1HSP90AA1ACMSDKDM4E
SCHEMBL5520487 0.79 PTPN5 (0.44) NUDT1BACE1HSP90AA1FEN1PTPN5
SCHEMBL15512040 0.79 TRPA1 (0.48) NUDT1BACE1HSP90AA1ACMSDKDM4E
SCHEMBL9138938 0.78 NUDT1 (0.34) NUDT1BACE1HSP90AA1ACMSDKDM4E
Ethane SCHEMBL27596791 0.78 APP (0.40) NUDT1BACE1HSP90AA1ACMSDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10577449-B2 Phenolic-hydroxyl-group-containing novolac resin and resist film DIC CORPORATION (JP) 2020-03-03 — — US disclosed
US-10414850-B2 Resin containing phenolic hydroxyl groups, and resist film DIC CORPORATION (JP) 2019-09-17 — — US disclosed
US-20190077901-A1 NOVOLAC-TYPE PHENOLIC HYDROXY GROUP-CONTAINING RESIN, AND RESIST FILM DIC CORPORATION (JP) 2019-03-14 — — US disclosed
US-10162260-B2 Photosensitive resin composition, protective film, and liquid crystal display element CHI MEI CORPORATION (TW) 2018-12-25 — — US disclosed
US-20180346635-A1 NOVOLAC RESIN AND RESIST FILM DIC CORPORATION (JP) 2018-12-06 — — US disclosed
US-20180334523-A1 NOVOLAC RESIN AND RESIST FILM DIC CORPORATION (JP) 2018-11-22 — — US disclosed
US-20180327533-A1 RESIN CONTAINING PHENOLIC HYDROXYL GROUPS, AND RESIST FILM DIC CORPORATION (JP) 2018-11-15 — — US disclosed
US-9975830-B2 Compound containing modified phenolic hydroxy group, method for producing compound containing modified phenolic hydroxy group, photosensitive composition, resist material, and resist coating film DIC CORPORATION (JP) 2018-05-22 — — US disclosed
US-20180134834-A1 PHENOLIC-HYDROXYL-GROUP-CONTAINING NOVOLAC RESIN AND RESIST FILM DIC CORPORATION (JP) 2018-05-17 — — US disclosed
US-9963536-B2 Phenolic hydroxyl group-containing resin, production method therefor, photosensitive composition, resist material, coating film, curable composition and cured product thereof, and resist underlayer film DIC CORPORATION (JP) 2018-05-08 — — US disclosed
EP-1469353-A1 TWO-LAYER FILM AND METHOD OF FORMING PATTERN WITH THE SAME JSR Corporation (JP) 2004-10-20 — — EP disclosed
US-20040131963-A1 Two-layer film and method of forming pattern with the same JSR CORPORATION (JP) 2004-07-08 — — US disclosed
US-5677102-A DISSOLVING AN ALKALI SOLUBLE RESIN AND A QUINONEDIAZIDE GROUP CONTAINING COMPOUND; HEATING TOKYO OHKA KOGYO CO., LTD. (JP) 1997-10-14 — — US disclosed
US-5604077-A MIXTURE OF ALKALI-SOLUBLE NOVOLAK AND A QUINONE DIAZIDE PHOTOSENSITIZER; HEAT RESISTANCE, RESOLUTION, ANTIFOULING AGENTS TOKYO OHKA KOGYO CO., LTD. (JP) 1997-02-18 — — US disclosed
US-5601961-A QUINONE DIAZIDE GROUP-CONTAINING COMPOUND AS PHOTOSENSITIZING AGENT, ALKALI-SOLUBLE RESINOUS INGREDIENT AS FILM-FORMING AGENT MADE FROM A BLEND OF AT LEAST TWO NOVOLAK-TYPE RESINS FROM M-AND P-CRESOL, A XYLENOL AND A TRIMETHYLPHENOL TOKYO OHKA KOGYO CO., LTD. (JP) 1997-02-11 — — US disclosed
US-5576138-A MIXTURE OF RESIN, PHOTOSENSITIZER AND BENZOPHENONE COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 1996-11-19 — — US disclosed
US-5501936-A IMPROVED RESOLUTION OF VERY FINE PATTERNS TOKYO OHKA KOGYO CO., LTD. (JP) 1996-03-26 — — US disclosed
US-5478692-A Fine patterning for electronics TOKYO OHKA KOGYO CO., LTD. (JP) 1995-12-26 — — US disclosed
US-5434031-A Positive-working naphthoquinone diazide photoresist composition containing specific hydroxy compound additive TOKYO OHKA KOGYO CO., LTD. (JP) 1995-07-18 — — US disclosed
US-5401605-A Positive working photosensitive resin composition containing 1,2-naphthoquinone diazide esterification product of triphenylmethane compound TOKYO OHKA KOGYO CO., LTD. (JP) 1995-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180134834-A1 PHENOLIC-HYDROXYL-GROUP-CONTAINING NOVOLAC RESIN AND RESIST FILM HACL2, ASH2L, HEATR1 NUDT1 3338/4885BACE1 2648/4885HSP90AA1 53/4885
US-20180334523-A1 NOVOLAC RESIN AND RESIST FILM ASH2L, PRRC2C, ACSL1 NUDT1 4033/4885BACE1 1977/4885HSP90AA1 606/4885
US-10577449-B2 Phenolic-hydroxyl-group-containing novolac resin and resist film HACL2, ASH2L, HEATR1 NUDT1 3338/4885BACE1 2648/4885HSP90AA1 53/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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