Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2381142 | 0.85 | KMT2A (0.52) | KMT2ANPSR1ALDH1A1GAAMAPT | |
| SCHEMBL4018757 | 0.83 | NPSR1 (0.59) | KMT2ANPSR1ALDH1A1GAAMAPT | |
| SCHEMBL1520822 | 0.83 | NPSR1 (0.68) | KMT2ANPSR1ALDH1A1GAAMAPT | |
| SCHEMBL2204065 | 0.80 | NPSR1 (0.64) | KMT2ANPSR1ALDH1A1GAAMAPT | |
| SCHEMBL2226834 | 0.79 | APLNR (0.63) | NPSR1ALDH1A1GAAHPGDHTT | |
| SCHEMBL14750301 | 0.79 | POLB (0.50) | KMT2ANPSR1ALDH1A1GAAMAPT | |
| SCHEMBL14670856 | 0.78 | HPGD (0.70) | KMT2ANPSR1ALDH1A1GAAMEN1 | |
| SCHEMBL27766295 | 0.78 | ATM (0.60) | KMT2ANPSR1GAAMAPTMEN1 | |
| SCHEMBL12884376 | 0.78 | LMNA (0.72) | KMT2ANPSR1ALDH1A1MAPTMEN1 | |
| SCHEMBL2938380 | 0.77 | KMT2A (0.69) | KMT2ANPSR1ALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104902932-A | Chemical indicating composition, autoclave tape, and method for preparing autoclave tape | 3M INNOVATIVE PROPERTIES CO | 2015-09-09 | — | — | CN | claimed |
| US-20230320941-A1 | DENTAL COMPOSITION, KIT AND METHOD FOR USE AS ALTERNATIVE RESTORATIVE MATERIAL TO DENTAL AMALGAM | SDI LIMITED (AU) | 2023-10-12 | — | — | US | disclosed |
| CN-116600766-A | Dental composition, kit and method for use as restorative material for replacement of dental amalgam | SDI有限公司 | 2023-08-15 | — | — | CN | disclosed |
| EP-4196077-A1 | DENTAL COMPOSITION, KIT AND METHOD FOR USE AS ALTERNATIVE RESTORATIVE MATERIAL TO DENTAL AMALGAM | Sdi Limited (AU) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022032351-A1 | DENTAL COMPOSITION, KIT AND METHOD FOR USE AS ALTERNATIVE RESTORATIVE MATERIAL TO DENTAL AMALGAM | SDI LIMITED (AU) | 2022-02-17 | — | — | WO | disclosed |
| US-20210186906-A1 | METHODS, COMPOSITIONS, AND KITS FOR TREATING PAIN AND PRURITIS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-06-24 | — | — | US | disclosed |
| US-9353089-B2 | Compositions and methods for the treatment of malaria | SAINT LOUIS UNIVERSITY (US) | 2016-05-31 | — | — | US | disclosed |
| CN-104902932-A | Chemical indicating composition, autoclave tape, and method for preparing autoclave tape | 3M INNOVATIVE PROPERTIES CO | 2015-09-09 | — | — | CN | disclosed |
| WO-2014160775-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MALARIA | SAINT LOUIS UNIVERSITY (US) | 2014-10-02 | — | — | WO | disclosed |
| US-20140296532-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MALARIA | GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2014-10-02 | — | — | US | disclosed |
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | ARENA PHARMACEUTICALS, INC. | 2007-01-11 | — | — | US | disclosed |
| CN-1359373-A | 6- [ [ (aryl and heteroaryl) oxy ] methyl ] -naphthyl-2-carboximidamide derivatives, process for their preparation and their use in therapy | SANOFI SYNTHELABO (FR) | 2002-07-17 | — | — | CN | disclosed |
| WO-2000012492-A1 | BENZOXAZINE DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |
| US-4116957-A | ANTIBIOTIC, ANTIBACTERIAL | ARCHIFAR INDUSTRIE CHIMICHE DEL TRENTINO S.P.A. (IT) | 1978-09-26 | — | — | US | disclosed |
| US-3991008-A | METHACRYLATE MONOMER, HYDROPEROXIDE OXIDIZER, THIOUREA REDUCING AGENT | THE KENDALL COMPANY (US) | 1976-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | MCHR1, GPR119, MCHR2 | KMT2A 792/4885NPSR1 62/4885ALDH1A1 2069/4885 |
| US-20140296532-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MALARIA | BACE2, DNPEP, ACE | KMT2A 960/4885NPSR1 2755/4885ALDH1A1 1822/4885 |
| US-20210186906-A1 | METHODS, COMPOSITIONS, AND KITS FOR TREATING PAIN AND PRURITIS | TRPV1, TRPV2, TRPV3 | KMT2A 2886/4885NPSR1 216/4885ALDH1A1 3850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.