Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.39 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10887314 | 0.86 | ALDH1A1 (0.63) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL9814732 | 0.84 | KDM4E (0.48) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL5528033 | 0.83 | ALDH1A1 (0.62) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL30775588 | 0.76 | MAPT (0.67) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL29140301 | 0.76 | MAPT (0.67) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL30057806 | 0.71 | LMNA (0.48) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL486125 | 0.71 | MAPT (0.73) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL14366663 | 0.70 | MGLL (0.61) | ALDH1A1MAPTGAALMNAKDM4E | |
| SCHEMBL10651976 | 0.70 | ALDH1A1 (0.47) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL486624 | 0.69 | MAPT (1.00) | ALDH1A1MAPTGAALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260557-B1 | ASYMMETRIC 1:2 METAL COMPLEX DYESTUFS | BAYER AG (DE) | 1991-11-27 | — | — | EP | disclosed |
| EP-0267385-B1 | ASYMMETRIC 1:2-CHROMIUM COMPLEX DYESTUFFS | BAYER AG (DE) | 1991-10-09 | — | — | EP | disclosed |
| EP-0267385-A2 | Asymmetric 1:2-chromium complex dyestuffs | BAYER AG (DE) | 1988-05-18 | — | — | EP | disclosed |
| EP-0260557-A2 | Asymmetric 1:2 metal complex dyestufs | BAYER AG (DE) | 1988-03-23 | — | — | EP | disclosed |
| EP-0072501-B1 | ASYMMETRIC 1:2 CHROMIUM-COMPLEX DYESTUFFS | BAYER AG (DE) | 1986-12-03 | — | — | EP | disclosed |
| US-4029643-A | Chromium containing azo dyes | NIPPON KAYAKU KABUSHIKI KAISHA (JA) | 1977-06-14 | — | — | US | disclosed |