Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 2/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31658933 | 0.90 | S100A4 (0.44) | S100A4TRPV1ADRA2AADRA2BADRA2C | |
| SCHEMBL5249670 | 0.83 | MAPT (0.56) | S100A4MAPTGSK3BMEN1NPC1 | |
| SCHEMBL8536034 | 0.82 | ESR1 (0.43) | MAPTCSNK1A1TYRO3DYRK1BCCNB2 | |
| SCHEMBL8540810 | 0.82 | TSHR (0.50) | MAPTMMP13MMP2MMP9MMP8 | |
| SCHEMBL8537593 | 0.82 | GSK3B (0.47) | MAPTCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL10680334 | 0.81 | MAPT (0.39) | MAPTCSNK1A1TYRO3DYRK1BCCNB2 | |
| SCHEMBL1303527 | 0.80 | CSNK1A1 (0.50) | PTGESMAPTCSNK1A1TYRO3DYRK1B | |
| SCHEMBL8536429 | 0.78 | VCAM1 (0.50) | MAPTMEN1KMT2A | |
| SCHEMBL8536432 | 0.78 | ALDH1A1 (0.48) | ADRA2AADRA2CMAPTAMY1AGSK3B | |
| SCHEMBL204357 | 0.78 | S100A4 (0.61) | S100A4TRPV1MAPTRAB9AGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757591-A1 | CINNAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |