Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.45 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539529 | 0.84 | GPR35 (0.49) | MAPTMEN1KMT2ANPC1HSP90AA1 | |
| SCHEMBL8540776 | 0.83 | AMY1A (0.48) | MAPTMEN1KMT2ANPC1HSP90AA1 | |
| SCHEMBL8540810 | 0.83 | TSHR (0.50) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL31463535 | 0.83 | AMY1A (0.48) | MAPTMEN1KMT2ANPC1HSP90AA1 | |
| SCHEMBL8537593 | 0.83 | GSK3B (0.47) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8536034 | 0.83 | ESR1 (0.43) | MAPTMEN1KMT2ANPC1HSP90AA1 | |
| SCHEMBL5747525 | 0.83 | MEN1 (0.46) | MAPTMEN1KMT2ANPC1HSP90AA1 | |
| SCHEMBL5528175 | 0.83 | S100A4 (0.46) | MAPTMEN1KMT2ANPC1HSP90AA1 | |
| SCHEMBL10680334 | 0.82 | MAPT (0.39) | MAPTMEN1KMT2ANPC1HSP90AA1 | |
| SCHEMBL4055359 | 0.82 | HSD17B10 (0.49) | MAPTMEN1KMT2ANPC1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546157-A4 | PHENYL-AZA-BENZIMIDAZOLE COMPOUNDS FOR MODULATING IgE AND INHIBITING CELLULAR PROLIFERATION | AVANIR PHARMACEUTICALS (US) | 2007-02-28 | — | — | EP | disclosed |
| EP-1546157-A2 | PHENYL-AZA-BENZIMIDAZOLE COMPOUNDS FOR MODULATING IgE AND INHIBITING CELLULAR PROLIFERATION | Avanir Pharmaceuticals (US) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004024897-A2 | PHENYL-AZA-BENZIMIDAZOLE COMPOUNDS FOR MODULATING IgE AND INHIBITING CELLULAR PROLIFERATION | AVANIR PHARMACEUTICALS (US) | 2004-03-25 | — | — | WO | disclosed |