Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ribose (Furanose) SCHEMBL4391869 | 0.82 | ADA (0.47) | LMNAALDH1A1SMN1; SMN2POLBPNP | |
| 2,6-Diaminopurine SCHEMBL8153506 | 0.80 | HIF1A (0.42) | LMNAALDH1A1GMNNTP53NFKB1 | |
| 2,6-Diaminopurine SCHEMBL10774599 | 0.80 | HIF1A (0.42) | LMNAALDH1A1GMNNTP53NFKB1 | |
| 2-Aminopurine SCHEMBL28775710 | 0.80 | ALDH1A1 (0.59) | LMNAALDH1A1GMNNTP53NFKB1 | |
| SCHEMBL3664019 | 0.78 | PYGL (0.41) | LMNAGMNNNFKB1BLMPMP22 | |
| SCHEMBL2914676 | 0.78 | PYGL (0.41) | LMNAGMNNNFKB1BLMPMP22 | |
| SCHEMBL10666441 | 0.78 | PYGL (0.41) | LMNAGMNNNFKB1BLMPMP22 | |
| SCHEMBL6935271 | 0.78 | PYGL (0.41) | LMNAGMNNNFKB1BLMPMP22 | |
| SCHEMBL17364274 | 0.78 | PYGL (0.41) | LMNAGMNNNFKB1BLMPMP22 | |
| SCHEMBL3727543 | 0.78 | PYGL (0.41) | LMNAGMNNNFKB1BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297787-B2 | Process for preparing N6 substituted aminopurine ribofuranose nucleosides | GLAXO GROUP LIMITED (GB) | 2007-11-20 | — | — | US | disclosed |
| US-7297787-B2 | Process for preparing N6 substituted aminopurine ribofuranose nucleosides | GLAXO GROUP LIMITED (GB) | 2007-11-20 | — | — | US | disclosed |
| EP-1370569-B1 | PROCESS FOR PREPARING N6-SUBSTITUTED AMINOPURINE RIBOFURANOSE NUCLEOSIDES | GLAXO GROUP LTD (GB) | 2005-08-31 | — | — | EP | disclosed |
| US-20050176949-A1 | Process for preparing N6 substituted aminopurine ribofuranose nucleosides | GLAXO GROUP LIMITED (GB) | 2005-08-11 | — | — | US | disclosed |
| US-20050176949-A1 | Process for preparing N6 substituted aminopurine ribofuranose nucleosides | GLAXO GROUP LIMITED (GB) | 2005-08-11 | — | — | US | disclosed |
| EP-1370569-A1 | PROCESS FOR PREPARING N6-SUBSTITUTED AMINOPURINE RIBOFURANOSE NUCLEOSIDES | GLAXO GROUP LIMITED (GB) | 2003-12-17 | — | — | EP | disclosed |
| EP-1370569-A1 | PROCESS FOR PREPARING N6-SUBSTITUTED AMINOPURINE RIBOFURANOSE NUCLEOSIDES | GLAXO GROUP LIMITED (GB) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002074781-A1 | PROCESS FOR PREPARING N6-SUBSTITUTED AMINOPURINE RIBOFURANOSE NUCLEOSIDES | GLAXO GROUP LIMITED (GB) | 2002-09-26 | — | — | WO | disclosed |
| WO-2002074781-A1 | PROCESS FOR PREPARING N6-SUBSTITUTED AMINOPURINE RIBOFURANOSE NUCLEOSIDES | GLAXO GROUP LIMITED (GB) | 2002-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176949-A1 | Process for preparing N6 substituted aminopurine ribofuranose nucleosides | ADORA3, NUDT1, ADORA1 | LMNA 1864/4885ALDH1A1 1388/4885GMNN 550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.