Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RPA1 | P27694 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2811220 | 0.87 | ALDH1A1 (0.48) | LDHAFABP4ALDH1A1HNF4AKDM4E | |
| SCHEMBL21881930 | 0.80 | AKT2 (0.43) | ALDH1A1HTTLMNAKMT2AMAPT | |
| SCHEMBL3078886 | 0.76 | HDAC1 (0.44) | FABP4ALDH1A1POLBKDM4ELMNA | |
| SCHEMBL4363981 | 0.76 | FABP4 (0.68) | LDHAFABP4ALDH1A1MYCPOLB | |
| SCHEMBL29598295 | 0.75 | LDHA (0.46) | LDHAFABP4ALDH1A1MYCHNF4A | |
| Hydrochloric Acid SCHEMBL7605502 | 0.74 | FABP4 (0.66) | LDHAFABP4ALDH1A1MYCPOLB | |
| SCHEMBL28723383 | 0.73 | KDM4E (0.43) | ALDH1A1POLBKDM4ELMNAALOX15 | |
| SCHEMBL10205843 | 0.73 | AKT2 (0.42) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL10365151 | 0.73 | MKNK1 (0.56) | ALDH1A1KDM4EHTTLMNAALOX15 | |
| SCHEMBL6577587 | 0.72 | GABRP (0.42) | LDHAALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1855670-A2 | BENZAZOLE POTENTIATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Merck & Co., Inc. (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006091496-A2 | BENZAZOLE POTENTIATORS OF METABOTROPIC GLUTAMATE RECEPTORS | MERCK & CO., INC. (US) | 2006-08-31 | — | — | WO | disclosed |