SCHEMBL2811220

SCHEMBL2811220

O=C(O)c1cncc(C(=O)O)c1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
ALOX15 P16050 1/20 0.48
HNF4A P41235 3/20 0.47
LDHA P00338 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
PTPN1 P18031 1/20 0.43
ACMSD Q8TDX5 2/20 0.42
DHFR P00374 1/20 0.42
MCL1 Q07820 1/20 0.42
CDC25B P30305 1/20 0.42
ATM Q13315 1/20 0.42
KDM4E B2RXH2 3/20 0.42
MAPT P10636 2/20 0.42
PIM1 P11309 1/20 0.42
GFER P55789 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MKNK1 Q9BUB5 1/20 0.42
MKNK2 Q9HBH9 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5532397 0.87 LDHA (0.50) ALDH1A1ALOX15HNF4ALDHAMEN1
SCHEMBL10365151 0.84 MKNK1 (0.56) ALDH1A1ALOX15KDM4EMAPTPIM1
SCHEMBL28723383 0.81 KDM4E (0.43) ALDH1A1ALOX15MEN1KMT2AKDM4E
SCHEMBL3078886 0.80 HDAC1 (0.44) ALDH1A1KDM4EGFERSMN1; SMN2LMNA
SCHEMBL70098 0.79 HNF4A (0.63) ALDH1A1ALOX15HNF4AACMSDCDC25B
SCHEMBL30205037 0.79 LMNA (0.49) ALDH1A1ALOX15MEN1KMT2AATM
SCHEMBL10634933 0.78 CAMKK2 (0.44) KMT2AACMSDKDM4ETDP1SMN1; SMN2
SCHEMBL10634858 0.78 CAMKK2 (0.44) KMT2AACMSDKDM4ETDP1SMN1; SMN2
SCHEMBL332581 0.77 ALDH1A1 (0.57) ALDH1A1ALOX15HNF4AACMSDDHFR
SCHEMBL11233688 0.76 LDHA (0.47) ALDH1A1ALOX15HNF4ALDHAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
EP-4204100-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE L'OREAL (FR) 2023-07-05 EP disclosed
CN-116322616-A Hair lightening compositions providing damage protection and sensory benefits and methods of use 欧莱雅 2023-06-23 CN disclosed
US-11559474-B2 Hair lightening compositions and methods of use L'OREAL (FR) 2023-01-24 US disclosed
WO-2022047081-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE HENRY DEREK (US) 2022-03-03 WO disclosed
WO-2018119500-A1 VISCOELASTIC COSMETIC COMPOSITIONS L'OREAL (FR) 2018-07-05 WO disclosed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US disclosed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 US disclosed
US-4923686-A Process for the extraction of metal values IMPERIAL CHEMICAL INDUSTRIES (GB) 1990-05-08 US disclosed
US-4775763-A PYRIDINE ESTER OR AMIDE FOR HYDROMETALLURGY IMPERIAL CHEMICAL INDUSTRIES (GB) 1988-10-04 US disclosed
US-4683310-A RECOVERING METALS FROM ORES IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) 1987-07-28 US disclosed
EP-0057797-B1 PROCESS FOR THE EXTRACTION OF METAL VALUES AND NOVEL METAL EXTRACTANTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-06-25 EP disclosed
US-4525330-A SOLVENT EXTRACTION USING ESTER-SUBSTITUTED PYRIDINE OF AQUEOUS HALIDE-CONTAINING SOLUTIONS OF COPPER SALTS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1985-06-25 US disclosed
EP-0057797-A2 Process for the extraction of metal values and novel metal extractants IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-08-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 ALDH1A1 1901/4885ALOX15 914/4885HNF4A 4816/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB ALDH1A1 4765/4885ALOX15 608/4885HNF4A 4565/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA ALDH1A1 1510/4885ALOX15 383/4885HNF4A 3980/4885
US-11559474-B2 Hair lightening compositions and methods of use TYR, ALAD, CYBA ALDH1A1 448/4885ALOX15 1704/4885HNF4A 4448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.