Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.34 |
| ▸ | CLK1 | P49759 | 2/20 | 0.34 |
| ▸ | CLK3 | P49761 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4089582 | 0.86 | KMT2A (0.39) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL4757355 | 0.80 | PYGM (0.39) | ALDH1A1GRIN1GRIN2AGRIN2BHTT | |
| SCHEMBL31506469 | 0.80 | CA1 (0.39) | KDM4EALDH1A1TSHRRAB9AMAPT | |
| SCHEMBL4757340 | 0.72 | NOTUM (0.34) | CCR2L3MBTL1 | |
| SCHEMBL4757333 | 0.72 | OPRM1 (0.36) | ALDH1A1HPGDTSHRCCR2NPSR1 | |
| SCHEMBL31195695 | 0.72 | ELANE (0.40) | KDM4EALDH1A1TSHRRAB9AGLA | |
| SCHEMBL11390110 | 0.68 | TDP1 (0.37) | KDM4ETDP1ALDH1A1HPGDNPSR1 | |
| SCHEMBL4758337 | 0.67 | HSD11B1 (0.36) | TSHRCCR2OPRM1 | |
| SCHEMBL295414 | 0.63 | SMN1; SMN2 (0.57) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| Hydrochloric Acid SCHEMBL11848402 | 0.62 | AKR1C3 (0.55) | KDM4EHPGDTSHRRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858325-A2 | COMPOUNDS FOR INHIBITING BETA-AMYLOID PRODUCTION AND METHODS OF IDENTIFYING THE COMPOUNDS | Roskamp Research LLC (US) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006074419-A2 | COMPOUNDS FOR INHIBITING BETA-AMYLOID PRODUCTION AND METHODS OF IDENTIFYING THE COMPOUNDS | ROSKAMP RESEARCH LLC (US) | 2006-07-13 | — | — | WO | disclosed |