Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1337898 | 0.89 | CA12 (0.48) | TSHRCYP2D6CYP2C9CA2CA4 | |
| SCHEMBL14420676 | 0.89 | TSHR (0.49) | TSHRCYP2D6CYP2C9CA2CA4 | |
| SCHEMBL6161536 | 0.85 | SIGMAR1 (0.45) | TSHRCYP2D6CYP2C9GAAALDH1A1 | |
| SCHEMBL14475375 | 0.82 | ACHE (0.46) | TSHRGAAALDH1A1TDP1USP2 | |
| SCHEMBL6162787 | 0.78 | SIGMAR1 (0.56) | CYP2D6 | |
| SCHEMBL19392089 | 0.73 | L3MBTL1 (0.40) | TSHRCYP2D6CYP2C9CFTRALDH1A1 | |
| SCHEMBL14965497 | 0.70 | ESR1 (0.39) | CA2CA4CA5AGAAHTT | |
| SCHEMBL15981889 | 0.70 | CA2 (0.33) | TSHRCA2CA4CA5ACFTR | |
| SCHEMBL31505112 | 0.70 | HTT (0.47) | TSHRCYP2D6CYP2C9CA2CA4 | |
| SCHEMBL29136506 | 0.70 | PARL (0.44) | TSHRCYP2D6CYP2C9CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780412-A1 | P-PIPERAZINE COMPOUNDS AS FLAME RETARDANTS | BASF SE (DE) | 2014-09-24 | — | — | EP | disclosed |
| US-20140243455-A1 | P-PIPERAZINE COMPOUNDS AS FLAME RETARDANTS | BASF SE (DE) | 2014-08-28 | — | — | US | disclosed |
| US-20140243455-A1 | P-PIPERAZINE COMPOUNDS AS FLAME RETARDANTS | BASF SE (DE) | 2014-08-28 | — | — | US | disclosed |
| US-20140243455-A1 | P-PIPERAZINE COMPOUNDS AS FLAME RETARDANTS | BASF SE (DE) | 2014-08-28 | — | — | US | disclosed |
| WO-2013072295-A1 | P-PIPERAZINE COMPOUNDS AS FLAME RETARDANTS | BASF SE (DE) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072295-A1 | P-PIPERAZINE COMPOUNDS AS FLAME RETARDANTS | BASF SE (DE) | 2013-05-23 | — | — | WO | disclosed |
| EP-1112314-B1 | FLAME RETARDANT RESIN COMPOSITIONS CONTAINING PHOSPHORAMIDES, AND METHOD FOR MAKING | GEN ELECTRIC (US) | 2007-07-04 | — | — | EP | disclosed |
| EP-1131378-B1 | FLAME RETARDANT RESIN COMPOSITIONS CONTAINING PHOSPHORAMIDES, AND METHOD FOR MAKING | GEN ELECTRIC (US) | 2005-02-23 | — | — | EP | disclosed |
| US-6569929-B2 | Containing thermoplastic resins | GENERAL ELECTRIC COMPANY | 2003-05-27 | — | — | US | disclosed |
| US-6433046-B1 | MIXTURE WITH THERMOPLASTIC RESIN AND FLAME RETARDANT; COMPUTER HOUSINGS, PANELS, APPLIANCES, AUTOMOBILES, SPORTS EQUIPMENT; MELT PROCESSABILITY HEAT RESISTANCE | GENERAL ELECTRIC COMPANY | 2002-08-13 | — | — | US | disclosed |
| US-6388046-B1 | MIXTURE CONTAINING THERMOPLASTIC RESIN | GENERAL ELECTRIC COMPANY | 2002-05-14 | — | — | US | disclosed |
| US-20020019466-A1 | Method to prepare phosphoramides, and resin compositions containing them | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2002-02-14 | — | — | US | disclosed |
| EP-1115786-A1 | FLAME RETARDANT RESIN COMPOSITIONS CONTAINING PHOSPHORAMIDES, AND METHOD FOR MAKING | GENERAL ELECTRIC COMPANY (US) | 2001-07-18 | — | — | EP | disclosed |
| EP-1112314-A1 | FLAME RETARDANT RESIN COMPOSITIONS CONTAINING PHOSPHORAMIDES, AND METHOD FOR MAKING | GENERAL ELECTRIC COMPANY (US) | 2001-07-04 | — | — | EP | disclosed |
| US-6228912-B1 | Flame retardant resin compositions containing phosphoramides and method for making | GENERAL ELECTRIC COMPANY | 2001-05-08 | — | — | US | disclosed |
| US-6221939-B1 | THERMOPLASTIC RESIN BLEND | GENERAL ELECTRIC COMPANY | 2001-04-24 | — | — | US | disclosed |
| WO-2000012611-A1 | FLAME RETARDANT RESIN COMPOSITIONS CONTAINING PHOSPHORAMIDES, AND METHOD FOR MAKING | GENERAL ELECTRIC COMPANY (US) | 2000-03-09 | — | — | WO | disclosed |
| WO-2000012614-A1 | FLAME RETARDANT RESIN COMPOSITIONS CONTAINING PHOSPHORAMIDES, AND METHOD FOR MAKING | GENERAL ELECTRIC COMPANY (US) | 2000-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019466-A1 | Method to prepare phosphoramides, and resin compositions containing them | PPA1, PHOSPHO1, PFAS | TSHR 4501/4885CYP2D6 4726/4885CYP2C9 4776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.