Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29435098 | 0.86 | ALDH1A1 (0.61) | ALOX5ALDH1A1KDM4EKMT2APKM | |
| SCHEMBL4537381 | 0.86 | ALDH1A1 (0.61) | ALOX5ALDH1A1KDM4EKMT2APKM | |
| SCHEMBL914240 | 0.84 | CA12 (0.59) | ALOX5ALDH1A1KDM4EKMT2APKM | |
| SCHEMBL7382482 | 0.84 | CA12 (0.47) | ALDH1A1KDM4EKMT2ACA12CA9 | |
| SCHEMBL3450041 | 0.83 | CA12 (0.43) | ALOX5ALDH1A1KDM4EKMT2ACA12 | |
| SCHEMBL7388942 | 0.83 | ALOX5 (0.43) | ALOX5ALDH1A1KDM4EKMT2ATSHR | |
| SCHEMBL5209415 | 0.82 | CCR2 (0.43) | ALOX5ALDH1A1KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL7697013 | 0.82 | NPC1 (0.41) | ALOX5ALDH1A1KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL7380758 | 0.82 | CA12 (0.47) | ALDH1A1KDM4EKMT2ACA12CA9 | |
| SCHEMBL7385872 | 0.82 | CA12 (0.47) | KDM4EKMT2ACA12CA9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1760054-A2 | Process for producing cyclic compound | Takeda Pharmaceutical Company Limited (JP) | 2007-03-07 | — | — | EP | disclosed |
| US-7038042-B2 | Process for producing cyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-05-02 | — | — | US | disclosed |
| US-20050096475-A1 | Process for producing cyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-05-05 | — | — | US | disclosed |
| US-6864367-B2 | Process for producing cyclic compound | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-03-08 | — | — | US | disclosed |
| US-6596758-B1 | Treatment of dislipidaemias, atherosclerosis and diabetes, to pharmaceutical compositions comprising them and to processes allowing the preparation of these compounds. | MERCK PATENT GMBH (DE) | 2003-07-22 | — | — | US | disclosed |
| EP-1140893-B1 | BENZOPYRANS AND BENZOXEPINES, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND PREPARATION PROCESS | MERCK PATENT GMBH (DE) | 2003-03-05 | — | — | EP | disclosed |
| US-20030040632-A1 | Process for producing cyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-02-27 | — | — | US | disclosed |
| EP-1266881-A1 | PROCESS FOR PRODUCING CYCLIC COMPOUND | Takeda Chemical Industries, Ltd. (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6369110-B1 | PROPHYLACTIC AGENT FOR DISEASES CAUSED BY THE ACCELERATION OF THE SODIUM/PROTON EXCHANGE TRANSPORT SYSTEM | SUMITOMO PHARMACEUTICALS COMPANY (JP) | 2002-04-09 | — | — | US | disclosed |
| EP-1140893-A1 | BENZOPYRANS AND BENZOXEPINES, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND PREPARATION PROCESS | MERCK PATENT GmbH (DE) | 2001-10-10 | — | — | EP | disclosed |
| EP-1083166-A1 | NOVEL SUBSTITUTED GUANIDINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-03-14 | — | — | EP | disclosed |
| WO-2000039113-A1 | BENZOPYRANS AND BENZOXEPINES, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND PREPARATION PROCESS | MERCK PATENT GMBH (DE) | 2000-07-06 | — | — | WO | disclosed |
| WO-1998055475-A1 | GUANIDINE DERIVIATIVES AS INHIBITORS OF NA+/H+ EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-10 | — | — | WO | disclosed |
| WO-1998016527-A1 | BENZOXEPINE DERIVATIVES WHICH PROMOTE RELEASE OF GROWTH HORMONE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030040632-A1 | Process for producing cyclic compound | CTH, DOHH, SLC39A11 | ALOX5 3076/4885ALDH1A1 3207/4885KDM4E 2097/4885 |
| US-20050096475-A1 | Process for producing cyclic compound | SLC39A11, CYP4F11, WEE1 | ALOX5 2231/4885ALDH1A1 3392/4885KDM4E 1121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.