Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | S100A4 | P26447 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3599344 | 0.88 | SMN1; SMN2 (0.47) | TDP1GPR35LOXL2ALDH1A1TSHR | |
| SCHEMBL8329812 | 0.88 | ALDH1A1 (0.48) | TDP1GPR35LOXL2ALDH1A1TSHR | |
| SCHEMBL28852174 | 0.86 | TDP1 (0.45) | TDP1GPR35LOXL2ALDH1A1TSHR | |
| SCHEMBL9203388 | 0.86 | TSHR (0.58) | TDP1GPR35LOXL2ALDH1A1TSHR | |
| SCHEMBL1161844 | 0.86 | TDP1 (0.45) | TDP1GPR35LOXL2ALDH1A1TSHR | |
| SCHEMBL29704492 | 0.86 | TDP1 (0.45) | TDP1GPR35LOXL2ALDH1A1TSHR | |
| SCHEMBL9196646 | 0.86 | GPR35 (0.56) | TDP1GPR35LOXL2ALDH1A1TSHR | |
| SCHEMBL4146683 | 0.86 | ALDH1A1 (0.51) | TDP1GPR35LOXL2ALDH1A1TSHR | |
| SCHEMBL6118566 | 0.83 | TDP1 (0.50) | TDP1GPR35ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL3844846 | 0.82 | TDP1 (0.44) | TDP1GPR35LOXL2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111217744-A | D-amino acid group NAD+Analogs, their synthesis and use | 中国科学院大连化学物理研究所 | 2020-06-02 | — | — | CN | disclosed |
| WO-2012068211-A1 | TRICYCLIC INHIBITORS OF PRO-MATRIX METALLOPROTEINASE ACTIVATION | JANSSEN PHARMACEUTICA NV (BE) | 2012-05-24 | — | — | WO | disclosed |
| US-20120129811-A1 | TRICYCLIC INHIBITORS OF PRO-MATRIX METALLOPROTEINASE ACTIVATION | JANSSEN PHARMACEUTICA N.V. (BE) | 2012-05-24 | — | — | US | disclosed |
| EP-1844189-A2 | SAMPLING SWAB | Smiths Detection Inc. (CA) | 2007-10-17 | — | — | EP | disclosed |
| WO-2007066240-A2 | SAMPLING SWAB | SMITHS DETECTION INC. (US) | 2007-06-14 | — | — | WO | disclosed |
| US-20040039040-A1 | Urea derivative and adhesive-molecule inhibitor containing the same as active ingredient | TORAY INDUSTRIES, INC. (JP) | 2004-02-26 | — | — | US | disclosed |
| EP-1323709-A1 | UREA DERIVATIVE AND ADHESIVE-MOLECULE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2003-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039040-A1 | Urea derivative and adhesive-molecule inhibitor containing the same as active ingredient | ICAM1, VCAM1, EPCAM | TDP1 4288/4885GPR35 699/4885LOXL2 1419/4885 |
| US-20120129811-A1 | TRICYCLIC INHIBITORS OF PRO-MATRIX METALLOPROTEINASE ACTIVATION | MMP1, MMP3, MMP13 | TDP1 365/4885GPR35 3668/4885LOXL2 1787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.