Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PRKDC | P78527 | 5/20 | 0.37 |
| ▸ | XRCC6 | P12956 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1699832 | 0.84 | ALDH1A1 (0.34) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7479031 | 0.82 | SMN1; SMN2 (0.43) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3821891 | 0.81 | MAPT (0.42) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8038479 | 0.79 | AHR (0.38) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8509702 | 0.78 | MEN1 (0.43) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7971543 | 0.77 | KIF11 (0.40) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL24620642 | 0.77 | LMNA (0.41) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8315808 | 0.77 | — | — | |
| SCHEMBL7562196 | 0.76 | AHR (0.36) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14267930 | 0.75 | KDM4E (0.40) | KDM4EMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975619-B1 | INTENSE COLOURING PHOTOCHROMIC 2H-NAPHTHO[1,2-b] PYRANS AND HETEROCYCLIC PYRANS | JAMES ROBINSON LTD (GB) | 2007-01-03 | — | — | EP | disclosed |
| EP-0975619-A1 | INTENSE COLOURING PHOTOCHROMIC 2$i(H)-NAPHTHO 1,2-$i(b)]PYRANS AND HETEROCYCLIC PYRANS | JAMES ROBINSON LIMITED (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998042695-A1 | INTENSE COLOURING PHOTOCHROMIC 2H-NAPHTHO[1,2-b]PYRANS AND HETEROCYCLIC PYRANS | JAMES ROBINSON LIMITED (GB) | 1998-10-01 | — | — | WO | disclosed |