Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MARS1 | P56192 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5117230 | 0.88 | CNR1 (0.59) | TAAR1CNR1TP53 | |
| SCHEMBL5037823 | 0.81 | CTSS (0.48) | TAAR1CNR1MEN1KMT2A | |
| SCHEMBL3054084 | 0.81 | FFAR1 (0.55) | TAAR1CNR1TP53NOS1NOS3 | |
| SCHEMBL12500551 | 0.80 | TAAR1 (0.65) | TAAR1TP53NOS1NOS3KDM4E | |
| SCHEMBL27598565 | 0.79 | TAAR1 (0.56) | TAAR1CNR1TP53NOS1NOS3 | |
| SCHEMBL28761382 | 0.79 | SIGMAR1 (0.68) | — | |
| SCHEMBL18191582 | 0.78 | MPO (0.54) | KDM4EMEN1KMT2AMPO | |
| SCHEMBL16246990 | 0.77 | ALDH1A1 (0.52) | KDM4EMARS1 | |
| SCHEMBL5503782 | 0.77 | NOS1 (0.50) | TAAR1NOS1NOS3KDM4EMPO | |
| SCHEMBL31114405 | 0.77 | TAAR1 (0.67) | TAAR1NOS1NOS3KDM4EMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797099-A1 | PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | Epix Delaware, Inc. (US) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006034511-A1 | PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | EPIX DELAWARE, INC. (US) | 2006-03-30 | — | — | WO | disclosed |