Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690795 | 0.88 | KDM4E (0.45) | KDM4ELMNAALDH1A1GAAPOLB | |
| SCHEMBL9691786 | 0.84 | KDM4E (0.41) | KDM4ELMNAALDH1A1GAAPOLB | |
| SCHEMBL7322941 | 0.75 | ADORA3 (0.58) | KDM4ELMNAALDH1A1GAAHSD17B10 | |
| SCHEMBL9369030 | 0.73 | CACNA1F (0.49) | KDM4ELMNAALDH1A1GAAPOLB | |
| SCHEMBL3503405 | 0.72 | KDM4E (1.00) | KDM4ELMNAALDH1A1GAAPOLB | |
| SCHEMBL11336599 | 0.72 | ADORA3 (0.42) | KDM4ELMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL9690862 | 0.71 | ALDH1A1 (0.54) | KDM4ELMNAALDH1A1GAAPOLB | |
| SCHEMBL8106730 | 0.67 | KDM4E (0.86) | KDM4ELMNAALDH1A1GAAPOLB | |
| SCHEMBL9831380 | 0.67 | KDM4E (0.86) | KDM4ELMNAALDH1A1GAAPOLB | |
| SCHEMBL8890327 | 0.67 | KDM4E (0.86) | KDM4ELMNAALDH1A1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225255-A1 | Use of Mitochondrially Targeted Antioxidant in the Treatment of Liver Diseases and Epithelial Cancers | ORIDIS BIOMED FORSCHUNGS-UND ENTWICKLUNGS GMBH (AT) | 2007-09-27 | — | — | US | disclosed |
| EP-1765413-A2 | MITOCHONDRIALLY TARGETED ANTIOXIDANTS IN THE TREATMENT OF LIVER DISEASES AND EPITHELIAL CANCERS | Oridis Biomed Forschungs- und Entwicklungs GmbH (AT) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006005759-A2 | MITOCHONDRIALLY TARGETED ANTIOXIDANTS IN THE TREATMENT OF LIVER DISEASES AND EPITHELIAL CANCERS | ORIDIS BIOMED FORSCHUNGS- UND ENTWICKLUNGS GMBH (AT) | 2006-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225255-A1 | Use of Mitochondrially Targeted Antioxidant in the Treatment of Liver Diseases and Epithelial Cancers | GLS2, PRDX5, GSR | KDM4E 1850/4885LMNA 2943/4885ALDH1A1 554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.