Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5565921 | 0.94 | KDM4E (0.54) | KDM4EALOX15HSD17B10ALDH1A1LMNA | |
| SCHEMBL9848007 | 0.94 | KDM4E (0.54) | KDM4EALOX15HSD17B10ALDH1A1LMNA | |
| SCHEMBL5565685 | 0.88 | KDM4E (0.51) | KDM4EALOX15HSD17B10ALDH1A1LMNA | |
| SCHEMBL5566273 | 0.84 | KDM4E (0.51) | KDM4EALOX15HSD17B10ALDH1A1LMNA | |
| SCHEMBL19501942 | 0.82 | ALOX15 (0.57) | KDM4EALOX15HSD17B10ALDH1A1LMNA | |
| SCHEMBL15130503 | 0.82 | ALOX15 (0.57) | KDM4EALOX15HSD17B10ALDH1A1LMNA | |
| SCHEMBL322219 | 0.82 | ALOX15 (0.57) | KDM4EALOX15HSD17B10ALDH1A1LMNA | |
| SCHEMBL677540 | 0.82 | KDM4E (0.55) | KDM4EALOX15HSD17B10ALDH1A1LMNA | |
| SCHEMBL5324787 | 0.82 | KDM4E (0.55) | KDM4EALOX15HSD17B10ALDH1A1LMNA | |
| SCHEMBL1260983 | 0.82 | KDM4E (0.55) | KDM4EALOX15HSD17B10ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100581589-C | Radiolabeled amino acid analogs, their preparation and use | MALLINCKRODT INC | 2010-01-20 | — | — | CN | claimed |
| US-7189383-B2 | Radioactively labelled amino acid analogues, their preparation and use | MALLINCKRODT INC. | 2007-03-13 | — | — | US | claimed |
| US-20060127306-A1 | Radioactively labelled amino acid analogues, their preparation and use | VRIJE UNIVERSITEIT BRUSSEL (BE) | 2006-06-15 | — | — | US | claimed |
| CN-1674943-A | Radiolabeled amino acid analogs, their preparation and use | MALLINCKRODT INC (US) | 2005-09-28 | — | — | CN | claimed |
| EP-1539250-A1 | RADIOACTIVELY LABELLED AMINO ACID ANALOGUES, THEIR PREPARATION AND USE | Mallinckrodt Inc. (US) | 2005-06-15 | — | — | EP | claimed |
| WO-2004110500-A1 | RADIOACTIVELY LABELLED AMINO ACID ANALOGUES, THEIR PREPARATION AND USE | MALLINCKRODT INC. (US) | 2004-12-23 | — | — | WO | claimed |
| CN-100581589-C | Radiolabeled amino acid analogs, their preparation and use | MALLINCKRODT INC | 2010-01-20 | — | — | CN | disclosed |
| US-20070081941-A1 | F-18 Labeled Amino Acid Analogs | MALLINCKRODT INC. (US) | 2007-04-12 | — | — | US | disclosed |
| US-7189383-B2 | Radioactively labelled amino acid analogues, their preparation and use | MALLINCKRODT INC. | 2007-03-13 | — | — | US | disclosed |
| US-20060127306-A1 | Radioactively labelled amino acid analogues, their preparation and use | VRIJE UNIVERSITEIT BRUSSEL (BE) | 2006-06-15 | — | — | US | disclosed |
| CN-1674943-A | Radiolabeled amino acid analogs, their preparation and use | MALLINCKRODT INC (US) | 2005-09-28 | — | — | CN | disclosed |
| EP-1539250-A1 | RADIOACTIVELY LABELLED AMINO ACID ANALOGUES, THEIR PREPARATION AND USE | Mallinckrodt Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004110500-A1 | RADIOACTIVELY LABELLED AMINO ACID ANALOGUES, THEIR PREPARATION AND USE | MALLINCKRODT INC. (US) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070081941-A1 | F-18 Labeled Amino Acid Analogs | BCAT1, BCAT2, SLC1A5 | KDM4E 3263/4885ALOX15 3003/4885HSD17B10 2197/4885 |
| US-20060127306-A1 | Radioactively labelled amino acid analogues, their preparation and use | BCAT1, BCAT2, SLC1A5 | KDM4E 3268/4885ALOX15 3080/4885HSD17B10 2307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.