Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | ACR | P10323 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2442995 | 0.90 | LMNA (0.76) | LMNATSHRHSD17B10HPGDALDH1A1 | |
| Methyl Salicylate SCHEMBL5565291 | 0.84 | LMNA (0.67) | LMNATSHRHSD17B10HPGDALDH1A1 | |
| Methyl Salicylate SCHEMBL26622127 | 0.82 | LMNA (0.73) | LMNATSHRHSD17B10HPGDALDH1A1 | |
| Methyl Salicylate SCHEMBL4113789 | 0.82 | LMNA (0.85) | LMNATSHRHSD17B10HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL31465587 | 0.82 | SCN1A (0.60) | LMNATSHRHSD17B10HPGDALDH1A1 | |
| SCHEMBL5706028 | 0.80 | SLC6A3 (0.77) | LMNATSHRHSD17B10HPGDALDH1A1 | |
| Methyl Salicylate SCHEMBL27586961 | 0.80 | LMNA (0.88) | LMNATSHRHSD17B10HPGDALDH1A1 | |
| SCHEMBL14394198 | 0.80 | ALDH1A1 (0.64) | LMNATSHRHSD17B10HPGDALDH1A1 | |
| Methyl Salicylate SCHEMBL29370254 | 0.78 | LMNA (1.00) | LMNATSHRHSD17B10HPGDALDH1A1 | |
| Methyl Salicylate SCHEMBL1872042 | 0.78 | LMNA (1.00) | LMNATSHRHSD17B10HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007100910-A2 | TRANSDERMAL PATCHES CONTAINING A NITRIC OXIDE-DONOR AND A SECOND ACTIVE AGENT AND ASSOCIATED METHODS | CURE THERAPEUTICS, INC. (US) | 2007-09-07 | — | — | WO | claimed |
| US-20070059351-A1 | Transdermal patches containing a nitric oxide-donor and a second active agent and associated methods | CURE THERAPEUTICS, INC. | 2007-03-15 | — | — | US | claimed |
| WO-2007100910-A2 | TRANSDERMAL PATCHES CONTAINING A NITRIC OXIDE-DONOR AND A SECOND ACTIVE AGENT AND ASSOCIATED METHODS | CURE THERAPEUTICS, INC. (US) | 2007-09-07 | — | — | WO | disclosed |
| US-20070059351-A1 | Transdermal patches containing a nitric oxide-donor and a second active agent and associated methods | CURE THERAPEUTICS, INC. | 2007-03-15 | — | — | US | disclosed |