Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.70 |
| ▸ | HPGD | P15428 | 4/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | ACR | P10323 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Salicylate SCHEMBL26622127 | 0.92 | LMNA (0.73) | LMNATSHRHSD17B10HPGDKDM4E | |
| SCHEMBL5565286 | 0.90 | LMNA (0.61) | LMNATSHRHSD17B10HPGDKDM4E | |
| SCHEMBL5706028 | 0.89 | SLC6A3 (0.77) | LMNATSHRHSD17B10HPGDKDM4E | |
| Methyl Salicylate SCHEMBL29370254 | 0.87 | LMNA (1.00) | LMNATSHRHSD17B10HPGDKDM4E | |
| Methyl Salicylate SCHEMBL1872042 | 0.87 | LMNA (1.00) | LMNATSHRHSD17B10HPGDKDM4E | |
| Methyl Salicylate SCHEMBL5312 | 0.87 | LMNA (1.00) | LMNATSHRHSD17B10HPGDKDM4E | |
| SCHEMBL13829204 | 0.86 | HSD17B10 (0.70) | LMNATSHRHSD17B10HPGDKDM4E | |
| SCHEMBL5706157 | 0.86 | SLC6A3 (0.72) | LMNATSHRHSD17B10HPGDKDM4E | |
| SCHEMBL13243352 | 0.86 | SLC6A3 (0.72) | LMNATSHRHSD17B10HPGDKDM4E | |
| SCHEMBL13813927 | 0.86 | SLC6A3 (0.72) | LMNATSHRHSD17B10HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10004753-B2 | Methods for treating tauopathy | THE J. DAVID GLADSTONE INSTITUTES (US) | 2018-06-26 | — | — | US | disclosed |
| US-9309233-B2 | Compositions and methods for the treatment of blood clotting disorders | CELLIX BIO PRIVATE LIMITED (IN) | 2016-04-12 | — | — | US | disclosed |
| US-20150119436-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF BLOOD CLOTTING DISORDERS | CELLIX BIO PRIVATE LIMITED (IN) | 2015-04-30 | — | — | US | disclosed |
| US-20150087697-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MUSCLE PAIN | KANDULA MAHESH (IN) | 2015-03-26 | — | — | US | disclosed |
| US-8440723-B2 | Metformin salts of salicylic acid and its congeners | MYLARI BANAVARA L (US) | 2013-05-14 | — | — | US | disclosed |
| US-20110217243-A1 | PHARMACEUTICAL IDENTIFICATION | PURDUE PHARMA L.P. (US) | 2011-09-08 | — | — | US | disclosed |
| US-7875215-B2 | A singlet oxygen scavenger, a radical trapping agent and an antioxidant; quaternary or amine salt derivatives of 4-hydroxy-3-cyclopenten-1,-2-dione; discoloration inhibition, light resistance; electrooptics, liquid crystal display, optical cards, optical recording media, and protective goggles | FUJIFILM CORPORATION (JP) | 2011-01-25 | — | — | US | disclosed |
| WO-2009155592-A1 | METHOD FOR PRODUCING PHENOLIC COMPOUND | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-12-23 | — | — | WO | disclosed |
| US-20090117266-A1 | NEAR-INFRARED-ABSORBING MATERIAL | FUJIFILM CORPORATION (JP) | 2009-05-07 | — | — | US | disclosed |
| US-20080169453-A1 | Near infrared ray absorbing material and near infrared ray absorbing filter | FUJIFILM CORPORATION (JP) | 2008-07-17 | — | — | US | disclosed |
| US-20080073626-A1 | A singlet oxygen scavenger, a radical trapping agent and an antioxidant; quaternary or amine salt derivatives of 4-hydroxy-3-cyclopenten-1,-2-dione; discoloration inhibition, light resistance; electrooptics, liquid crystal display, optical cards, optical recording media, and protective goggles | FUJIFILM CORPORATION (JP) | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119436-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF BLOOD CLOTTING DISORDERS | F2, F12, F5 | LMNA 2652/4885TSHR 1650/4885HSD17B10 524/4885 |
| US-10004753-B2 | Methods for treating tauopathy | MAPT, PYGB, CHAT | LMNA 958/4885TSHR 4730/4885HSD17B10 1173/4885 |
| US-20080169453-A1 | Near infrared ray absorbing material and near infrared ray absorbing filter | RRP12, MRPS22, H1-10 | LMNA 1943/4885TSHR 765/4885HSD17B10 3065/4885 |
| US-20150087697-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MUSCLE PAIN | TNNC1, MUSK, OPRK1 | LMNA 3792/4885TSHR 3401/4885HSD17B10 3042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.